Kyungbo Cefaclor Dry Syrup 25mg/mL (Cefaclor Hydrate)

Adult dose

For cefaclor, administer 250mg (active ingredient) every 8 hours orally. In cases of severe infections (such as pneumonia) or infections with low susceptibility, the dose may be doubled. For acute gonococcal urethritis, administer a single dose of 3g of this medication combined with 1g of probenecid.

Child dose

Administer 20mg (active ingredient) per kg of body weight divided every 8 hours. In cases of severe infections, otitis media, or infections with low susceptibility, the dosage may be increased to 40mg (active ingredient) per kg of body weight, with a maximum dose of

This medication works by binding to specific proteins and interfering with bacterial cell wall formation, killing the bacteria. Before using this medication, it should not be administered to patients who have experienced shock from this medication or are allergic to this medication or cephalosporin antibiotics. Patients with allergies to penicillin antibiotics, or those who frequently exhibit allergic symptoms such as bronchial asthma, rashes, or hives should use this medication cautiously. Special caution should be exercised when administering this medication to patients with severely impaired kidney function, elderly individuals, patients who have difficulty taking orally, and those with gastrointestinal diseases, as symptoms of vitamin K deficiency may occur; close observation of their condition is necessary. This medication can rarely trigger serious allergic reactions such as shock or anaphylaxis; if such symptoms occur, use should be stopped immediately and appropriate treatment should be sought. Severe reactions such as Stevens-Johnson syndrome or toxic epidermal necrolysis may occur, so skin condition should be closely monitored. Decreases in blood cell counts, liver dysfunction, or kidney impairment can occur, and regular check-ups should be conducted, with immediate reporting of any abnormal signs. Gastrointestinal symptoms may include abdominal pain, diarrhea, nausea, and vomiting; if severe colitis symptoms are present, administration must be stopped immediately. It may also affect the respiratory system, so if symptoms such as fever, cough, or difficulty breathing occur, consult healthcare professionals. Central nervous system side effects such as insomnia, dizziness, and hallucinations may rarely occur, and caution is necessary. This medication can increase the risk of bleeding due to vitamin K deficiency, so special caution is required in patients with bleeding tendencies. It may interact with other medications, especially probenecid, nephrotoxic drugs, anticoagulants, and oral contraceptives; therefore, inform healthcare professionals if taking such medications, as dosage adjustments or additional tests may be necessary. Pregnant or breastfeeding women should only use this medication if the benefits outweigh the risks, as its safety has not been fully established; caution should be taken as it may affect the infant while breastfeeding. In newborns less than 1 month old, the safety and efficacy of this medication have not been established, so it is advised to avoid use. Elderly individuals may exhibit side effects easily due to decreased bodily functions; thus, careful adjustment of the dosage and administration intervals is necessary. When using this medication, it is important to conduct susceptibility tests to prevent the emergence of resistant bacteria and to administer for only the necessary duration. Additionally, consider the possibility of infections caused by other microorganisms resistant to this medication when selecting appropriate treatment methods.

Serious side effects

Hives, swelling, difficulty breathing, generalized flushing, vascular swelling, syncope, hypertension, vasodilation, Stevens-Johnson syndrome, toxic epidermal necrolysis, shock, liver dysfunction (jaundice), acute renal failure, severe colitis, interstitial pneumonia, eosinophilic lung infiltration, severe allergic reactions, severe skin reactions, respiratory issues, liver dysfunction, severe swelling or urinary abnormalities.

Mild side effects

• Rash
• hives
• erythema
• itching
• fever
• lymphadenopathy
• arthralgia
• serum sickness-like reactions
• agranulocytosis
• neutropenia

This medication should be stored in a tightly sealed container that can block light, at a temperature between 1 to 30 degrees Celsius. Storing it this way helps maintain the drug's effectiveness.

Appearance

A pink dry syrup that is reconstituted at the time of use, contained in a high-density polyethylene bottle.

Package unit

100 mL × 10 bottle