Simbacor Tablet (Simvastatin)

Adult dose

1. Reduction of risk for cardiovascular diseases - Initial starting dose: 40 mg once daily 2. Hyperlipidemia - General initial starting dose: 20 mg once daily in the evening - For mild to moderate hypercholesterolemia: may start with 10 mg - Recommended to administer 5 to 40 mg once daily in the evening - Adjust dosage after 4 weeks of treatment and regularly check cholesterol levels Specific Patients

Child dose

3. Pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17) - Recommended initial dose: 10 mg once daily in the evening - Recommended dosage range: 10 to 40 mg once daily - Recommended maximum

This medication is used to lower blood cholesterol levels. Caution is required when taking this medication due to the risk of muscle problems. There is a higher risk of muscle damage, especially when taking high doses or in conjunction with certain other medications. Patients with liver function problems or abnormally high liver enzyme levels should not take this medication. Women who are pregnant or breastfeeding should not take this medication, and women who may become pregnant must use contraception during treatment. This medication should not be taken with certain strong medications, as it may increase the risk of muscle damage. Therefore, patients should inform healthcare providers of any other medications being taken. Patients with excessive alcohol intake or liver or kidney diseases should be especially cautious when taking this medication and should undergo regular checks to monitor their condition. Elderly patients and women are at a higher risk of muscle problems, so caution is necessary during treatment. If symptoms like muscle pain, muscle weakness, or discomfort occur while taking this medication, it is important to consult a doctor immediately, and medication can be stopped if necessary. This medication can affect liver function test results, so regular liver function tests are recommended. Furthermore, if prescribed a new medication during the time this medication is taken, it is important to inform healthcare providers and to avoid certain foods such as grapefruit juice. Blood sugar levels may increase while taking this medication, so patients at risk of diabetes should regularly check their blood sugar. Children or adolescents below certain ages should not take this medication, and should consult healthcare providers regarding its impact on growth and development. In case of overdose, contact a medical institution immediately for appropriate treatment. This medication should be kept out of reach of children and should be stored safely in its original container.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rashes with high fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, severe skin reactions, shortness of breath or difficulty breathing, asthma attacks, cough with fever accompanying respiratory abnormalities, jaundice (yellowing of skin or eyes), extreme lethargy, liver abnormalities (jaundice), sudden and severe

Mild side effects

• Abdominal pain
• weakness
• constipation
• diarrhea
• indigestion
• bloating
• nausea
• headache
• upper respiratory infection
• atrial fibrillation

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius.

Appearance

Yellow-brown oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle