Melobic Capsule (Meloxicam)

Adult dose

1. Acute exacerbations of osteoarthritis (degenerative arthritis): ○ Adults: Administer 7.5 mg of meloxicam orally once daily. If symptoms do not improve, the dose may be increased to up to 15 mg daily as needed. 2. Rheumatoid arthritis, ankylosing spondylitis: ○ Adults: Administer 15 mg of meloxicam orally once daily. The dose may be reduced to 7.5 mg daily depending on the response to treatment. Do not administer more than 15 mg of this medicine daily. The total daily dose should be taken all at once, with water or another beverage during a meal. ○ In elderly patients or those at increased risk of adverse reactions (e.g., a history of gastrointestinal disease or cardiovascular risk factors), treatment is usually started at a dose of 7.5 mg daily. ○ Patients with severe renal impairment undergoing hemodialysis should not receive more than 7.5 mg daily.

This medication may pose a risk of gastrointestinal bleeding if taken by individuals who regularly consume more than three drinks a day, thus consultation with a doctor or pharmacist is essential. This medication can affect the cardiovascular system, potentially leading to serious cardiovascular issues such as myocardial infarction or stroke, so patients with cardiovascular disease or risk factors must closely monitor for symptoms. If symptoms such as chest pain or shortness of breath occur, treatment must be discontinued immediately. Serious problems such as gastrointestinal bleeding, ulcers, and perforations may arise, so particular caution is warranted in individuals with a history of gastrointestinal disease or current gastrointestinal symptoms, needing immediate medical evaluation and treatment if symptoms appear. This medication can cause serious skin reactions, so if symptoms such as skin rash or mucosal damage occur, treatment should be stopped immediately, and medical consultation should be sought. It may influence kidney and liver function; thus, patients with kidney or liver disease should have regular function tests and discontinue use if abnormalities are found. This drug may impair fertility, so women planning to become pregnant should avoid using it, and it should also not be taken by women who are pregnant or breastfeeding. This medication should not be administered to patients with certain allergic reactions or those with gastrointestinal bleeding, perforations, severe liver or kidney impairment, heart failure, hypertension, inflammatory bowel disease, etc. When administered, careful consideration must be given to elderly patients or those with a history of gastrointestinal disease, blood disorders, or cardiovascular disease risk factors, and extra caution might be needed when driving or operating machinery. This medication has many interactions with other drugs, especially anticoagulants, lithium, methotrexate, diuretics, and antihypertensives, so it is essential to inform healthcare providers about all concurrent medications. In case of overdose, symptoms like drowsiness, nausea, vomiting, and gastrointestinal bleeding may occur, requiring immediate medical attention for appropriate treatment. Store this medication out of reach of children, and keep it sealed in its original container.

Gastrointestinal bleeding, serious cardiovascular thrombotic reactions, myocardial infarction, stroke, bleeding from the stomach or intestines, ulcers, perforation, exfoliative dermatitis, mucous membrane syndrome, toxic epidermal necrolysis, anaphylaxis, interstitial nephritis, glomerulonephritis, renal medullary necrosis, nephrotic syndrome, serum transaminase elevation, liver function elevation, increased plasma creatinine, increased blood urea nitrogen, aplastic anemia, bone marrow suppression, changes in blood cell counts, leukopenia, thrombocytopenia, anemia, decreased plasma iron, decreased hemoglobin, decreased hematocrit, neutrophilia, eosinophilia, basophilia, monocytosis, agranulocytosis, anaphylaxis, anaphylactoid reaction, malaise, confusion, loss of sense of direction, mood changes, mood disorders, insomnia, nightmares, anxiety, increased appetite, depression, nervousness, dizziness, drowsiness, headache, cranial discomfort, fatigue, lethargy, taste dysfunction, mental confusion, convulsions, sensory disturbances, tremors, blurred vision, visual impairment, conjunctivitis, foreign body sensation in the eye, scleral hemorrhage, tinnitus, palpitations, increased blood pressure, flushing, facial flushing, arrhythmia, tachycardia, hypotension, hypertension, myocardial infarction, angina pectoris, heart failure, vasculitis, cough, upper respiratory tract infection, asthma, bronchospasm, shortness of breath, dyspepsia, nausea, vomiting, abdominal pain, constipation, bloating, diarrhea, loss of appetite, peptic ulcer, occult gastrointestinal bleeding, overt gastrointestinal bleeding, stomatitis, gastritis, esophagitis, belching, dry mouth, thirst, angular cheilitis, occult blood in urine, gastric perforation, colitis, pancreatitis, melena, perforated peptic ulcer, hepatitis, angioedema, vesicular dermatitis, erythema multiforme, photosensitivity reactions, contact dermatitis, fixed drug eruption, urinary retention, changes in kidney function tests, total protein decrease, albumin decrease, proteinuria, glucosuria, increased urinary sediment, hematuria, sodium and water retention, hyperkalemia, acute renal failure, decreased urine output, frequent urination, urinary tract infection, interstitial nephritis, edema, lower extremity edema, lethargy, fever, facial edema, syncope, weight loss, weight gain, axillary pain, breast pain, arthralgia, low back pain, axillary pain, chest pain, stiffness, lower limb weakness, decreased fertility in women, dehydration

This medication is sensitive to light and should be stored in a container that protects it from light. Additionally, it is best stored at room temperature between 1 degree and 30 degrees Celsius to maintain effectiveness and safety.

Appearance

Hard capsule containing a light yellow powder in light green tops and bottoms

Package unit

30 capsules/bottle, 300 capsules/bottle