Efezon Tablets (Eperison Hydrochloride)

Adult dose

Adults: Eperison hydrochloride 50mg orally 3 times a day after meals. The dose may be adjusted appropriately according to age and symptoms.

This medication should not be used in certain patients. Specifically, it should not be administered to patients with hypersensitivity to this drug or those with severe myasthenia gravis. Additionally, it contains lactose, and patients with genetic lactose intolerance or related conditions should also avoid using it. When using this drug, caution should be exercised in patients with a history of drug hypersensitivity or impaired liver function. Some products contain the dye Yellow No. 5, which may cause allergic reactions, so care is needed if allergies to this component are present. Adverse reactions may rarely include shock, so if symptoms occur, administration should be immediately stopped, and appropriate treatment sought. Blood abnormalities such as liver dysfunction, kidney dysfunction, and anemia may also occur, so the patient's condition should be closely monitored. Skin rashes, itching, neuropsychiatric symptoms (insomnia, drowsiness, headaches, etc.), gastrointestinal symptoms (nausea, vomiting, diarrhea, etc.), and urinary symptoms may appear. Additionally, generalized symptoms such as weakness, dizziness, and decreased muscle tone have been reported, and, rarely, flushing, sweating, or edema may occur. Rarely, severe allergic reactions such as anaphylaxis or angioedema, and serious skin conditions such as Stevens-Johnson syndrome may occur, so symptoms such as fever, erythema, blisters, itching, conjunctival injection, and stomatitis should be carefully monitored. While taking this medication, weakness, drowsiness, or unsteadiness may occur, so it is advisable to reduce or stop the dosage if these symptoms appear. Due to drowsiness or decreased attention, driving a car or operating hazardous machinery should be avoided. Caution should be taken when used in combination with similar drugs or certain muscle relaxants, as coordination disturbances may occur. Women who are pregnant or may become pregnant should only use this medication if the benefits of treatment are deemed to outweigh the risks, as its safety during pregnancy has not been established. It is advisable to avoid using this drug while breastfeeding, and if it must be used, breastfeeding should be discontinued. The safety for children has not been sufficiently confirmed, so caution is needed when using it. Elderly patients may have decreased physiological function, so careful use, including dose reduction, is recommended.

Serious side effects

Shock (severe allergic reaction), anaphylactic reaction (severe allergic reaction), angioedema (severe swelling), toxic epidermal necrolysis and mucocutaneous-ocular syndrome (severe skin adverse reactions), liver dysfunction indicated by elevated ALT, AST, ALP, kidney dysfunction indicated by proteinuria and elevated BUN, anemia, severe rash with fever, blisters, skin peeling, oral/ocular mucosal pain

Mild side effects

• Rash
• itching
• insomnia
• drowsiness
• headache
• stiffness
• tremors
• nausea
• vomiting
• loss of appetite

This medication should be stored in a tightly sealed container to prevent moisture and air infiltration. Additionally, it should be kept away from direct sunlight and stored at room temperature between 1 to 30 degrees Celsius.

Appearance

For domestic use: white round film-coated tablet For export: light yellow to yellow round sugar-coated tablet

Package unit

For domestic use: 30 tablets/bottle, 500 tablets/bottle For export: 100 tablets (10 tablets/PTP packaging x 10)