Lipidu Tablets (Simvastatin)

Adult dose

1. For adult patients at high risk of coronary heart disease due to a history of coronary heart disease, diabetes, peripheral vascular disease, stroke, or other cerebrovascular diseases, administer 40 mg of simvastatin once daily. 2. For the treatment of hyperlipidemia, the usual starting dose is 20 mg once daily in the evening. Patients with mild to moderate hypercholesterolemia may start with 10 mg.

Child dose

For pediatric patients aged 10-17 with heterozygous familial hypercholesterolemia, administer 10 mg once daily in the evening. The recommended dosage range is 10-40 mg daily with a maximum dosage of 40 mg per day.

This medication primarily acts in the liver to lower blood cholesterol levels. However, it can cause muscle abnormalities, so if symptoms such as muscle pain or weakness occur during treatment, it must be reported to a doctor immediately. In particular, high-dose administration increases the risk of myopathy and rhabdomyolysis. This medication can affect liver function, thus it is safer not to use it in patients with liver disease or who have abnormally high liver enzyme levels. Women who are pregnant or may become pregnant, as well as nursing mothers, should not take this medication, and it should be discontinued immediately upon confirmation of pregnancy during treatment. There is a high potential for interaction with other medications, particularly with certain antifungals, antibiotics, immunosuppressants, calcium channel blockers, and some heart medications. It is advisable to avoid grapefruit juice during treatment and limit alcohol intake for liver health. Elderly patients, those with kidney or thyroid dysfunction, and patients with a history of muscle disease require careful monitoring when taking this medication. Regular blood tests to check liver function and muscle enzyme levels are recommended, and if abnormal findings are detected, consulting a physician is essential. This medication is not recommended for children under 10 years old or premenarche females. When taking this medication, it is important to inform the doctor or pharmacist about all currently taken medications, and to inform them when starting new medications. In the case of overdose, seek immediate medical treatment, and store this medication out of the reach of children.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, peeling skin, pain in mucous membranes of mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme fatigue, sudden and severe headache, thunderclap headache, seizures, altered consciousness, vision abnormalities, paralysis, urinary issues.

Mild side effects

• Abdominal pain
• asthenia
• constipation
• diarrhea
• dyspepsia
• bloating
• nausea
• headache
• upper respiratory infection
• atrial fibrillation

This medication should be stored in a tightly closed container to prevent exposure to air and moisture, ideally at room temperature between 1 and 30 degrees Celsius. Proper storage helps maintain the efficacy of the medication for a longer period.

Appearance

Brownish yellow oval film-coated tablets

Package unit

Packaging unit - 30 tablets/bottle