Simvarotin Tablets 20 mg (Simvastatin)

Adult dose

Adult patients at high risk for cardiovascular disease: 40 mg once daily. For hyperlipidemia: 5-40 mg once daily in the evening, initial dose is 20 mg (mild to moderate patients may start at 10 mg). For homozygous familial hypercholesterolemia: 40 mg once daily in the evening. Elderly: 20 mg once daily. When combined with verapamil, diltiazem, or dronedarone: do not exceed 10 mg daily. Amiodarone, amlodipine,

Child dose

Pediatric patients with heterozygous familial hypercholesterolemia (ages 10-17): 10 mg once daily in the evening. Recommended dosage range is 10-40 mg once daily, maximum 40 mg. Adjust dosage at intervals of 4 weeks or more.

This medication helps lower blood cholesterol levels to reduce the risk of cardiovascular disease. When taking this medication, it may cause muscle abnormalities, so if muscle pain, weakness, or tenderness occurs, consult a doctor immediately. Particularly, if taking a high dose of this medication, the risk of serious muscle injury such as myopathy or rhabdomyolysis increases, so caution is necessary. When taken with other medications that interact with this drug, the risk of muscle injury may increase, so be sure to notify your doctor and take appropriate measures. As it may affect liver function, it is better not to take this medication if there is liver disease or abnormal liver function test results. Women who are pregnant, may become pregnant, or are breastfeeding should not take this medication, and those planning a pregnancy should consult a doctor. Patients who consume alcohol excessively, have a history of liver or kidney disease, have hypothyroidism, or are elderly or female should be especially cautious when taking this medication. Regular blood tests are recommended to monitor liver function and muscle-related indicators while taking this medication. Avoid grapefruit juice as it may increase blood concentration and risk of side effects. If a new medication is prescribed or taken while using this medication, inform the prescribing doctor or pharmacist about the medications being taken. In case of overdose, visit a medical facility immediately for appropriate treatment and store the medication out of reach of children.

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, wheezing or difficulty breathing, asthma attacks, breathing difficulties accompanied by cough and fever, yellowing of skin or eyes (jaundice), systemic malaise, sudden and severe headache, thunderclap headache, seizures, confusion, vision disturbances, paralysis, significantly decreased urine output,

Mild side effects

• Abdominal pain
• fatigue
• constipation
• diarrhea
• dyspepsia
• bloating
• nausea
• headache
• upper respiratory infection
• atrial fibrillation

Store this medication in a tightly closed container to prevent air or moisture from entering, at room temperature between 1°C and 30°C. This way of storage can help maintain the efficacy of the medication.

Appearance

Brownish-yellow oval film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle