Glimet Tablet (Glimepiride)

Adult dose

Individual adjustments for each patient. Take without chewing, with more than half a cup of water. This medication is taken orally once a day. Administer before breakfast or immediately before the first meal. In monotherapy, patients starting new treatment take 1 mg of Glimepiride once daily, with possible increases of 1 mg every 1-2 weeks. Generally, a maximum of 4 mg is administered, but in certain cases, 6 mg may be necessary.

This medication should not be used in patients with insulin-dependent diabetes, diabetic ketoacidosis, or coma. It should also not be administered to patients who are allergic to this medication or sulfonylureas, and patients with severe liver or kidney impairment should not take it. Women who are pregnant or breastfeeding should avoid using this medication, and use should be avoided in patients undergoing surgery or in severe infection states. Patients with gastrointestinal disorders should be careful as there is a risk of hypoglycemia with this medication. This medication should also not be given to patients with hereditary lactose intolerance. During the first week of starting this medication, the risk of hypoglycemia is high, so careful blood sugar monitoring is necessary. Particularly, elderly patients, those in poor nutritional state, or patients with irregular eating patterns, and individuals who frequently consume alcohol should exercise extra caution. Patients with reduced kidney or liver function, those with other endocrine disorders, and patients taking multiple medications should also be managed carefully. Patients should inform their physician or pharmacist about symptoms and risk factors of hypoglycemia, and dosage adjustments should be made if necessary. This medication can cause hypoglycemic symptoms due to its blood sugar-lowering action, with symptoms including headache, severe hunger, nausea, fatigue, anxiety, confusion, drowsiness, and decreased consciousness. In severe cases of hypoglycemia, symptoms similar to a stroke may occur, so immediate treatment is necessary. Transient visual disturbances, gastrointestinal symptoms, liver function abnormalities, decreased blood cell counts, and allergic reactions have also been reported, so if any unusual symptoms occur, immediate consultation with medical personnel is required. To achieve optimal blood sugar control, this medication must be taken regularly, and dietary and exercise regimens should be followed. In case of hypoglycemia, consuming sugar or sugary beverages can quickly alleviate symptoms, so it is advisable to always carry some sugar. Since hypoglycemic symptoms may recur, careful monitoring and management according to the physician's instructions is necessary. When taking other medications together, the effect of this medication may change, so all medications being taken must be reported to the physician or pharmacist. Particularly, care must be taken regarding interactions with medications that affect the enzymes that break down this medication in the liver or have blood sugar-lowering or raising actions. Pregnant or breastfeeding women should avoid using this medication as it may harm the fetus or newborn, and should transition to insulin therapy if necessary. This medication is not used in children under 18 years of age as its safety and effectiveness have not been established. Elderly patients may have reduced kidney function, so careful determination of the dosage of this medication is required. In case of overdose, severe hypoglycemia may occur, and immediate visit to a medical institution for appropriate treatment is essential; measures such as inducing vomiting, gastric lavage, or intravenous glucose administration may be necessary. This medication should be stored out of reach of children and kept in its original container, as transferring to another container poses risks of misuse or degradation of quality.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, hypotension, shock, anaphylaxis, angioedema, skin and mucosal syndrome (Stevens-Johnson syndrome), liver dysfunction, jaundice, hepatitis, severe liver failure, thrombocytopenia, leukopenia, hemolytic anemia, erythrocytopenia, agranulocytosis, pancytopenia, aplastic anemia, thrombocytopenic purpura, severe allergic reactions, severe edema, hypoglycemic coma, severe hypoglycemic episodes.

Mild side effects

• Headache
• severe hunger
• nausea
• vomiting
• fatigue
• sleep disturbances
• anxiety
• aggression
• decreased concentration
• decreased agility or activity

This medication must be kept in a tightly sealed container to prevent exposure to air or moisture. Maintaining a storage temperature between 1 and 30 degrees Celsius at room temperature is important. This will help preserve the medication's effectiveness and safety.

Appearance

Domestic: Green rectangular tablet, Export: Dark blue rectangular tablet

Package unit

30 tablets/bottle, 100 tablets/bottle