Physionyl Solution 2.5%

Adult administration

Administered intraperitoneally for dialysis treatment. For adults, inject 2.0 to 2.5L once. Continuous Ambulatory Peritoneal Dialysis (CAPD) is performed 4 times a day (24 hours), and Automated Peritoneal Dialysis (APD) is done 4-5 cycles at night using a machine, with a maximum of 2 times during the day.

This medication is used for peritoneal dialysis, and sudden cessation of dialysis may pose a risk to life due to the inability to replace kidney function. It should not be used in patients with a hole in the diaphragm, abdominal burns, severe inflammation, surgery, or tumors in the abdomen. Moreover, it should be avoided in patients with bleeding risks, lactate metabolism disorders, severe electrolyte imbalances, severe lung disease, or sepsis. Those taking digitalis drugs, having glucose metabolism abnormalities, using colostomy, or on diuretics should have regular blood tests and status checks while using this medication. Pregnant women or immunocompromised patients, as well as patients with peritonitis, should be carefully administered, and caution is required in those with a corn allergy. Various side effects can occur during the peritoneal dialysis process, such as abdominal pain, peritonitis, electrolyte imbalance, hyperglycemia, and respiratory distress, so any abnormal symptoms should be reported to healthcare personnel immediately. The dialysis solution must be used in a sterile condition, and if the solution is discolored or cloudy, it should not be used. Overdosage may lead to dehydration, electrolyte disturbances, and hyperglycemia, which require immediate medical action. This medication should be used cautiously in pregnant or breastfeeding women, and dosage adjustments and caution are necessary for pediatric and elderly patients. Also, during peritoneal dialysis, various indicators such as weight, serum electrolytes, blood glucose, parathyroid hormone, etc., should be monitored regularly. There may be potential interactions with other medications, so if other medications are taken, consulting healthcare professionals is crucial. When storing, keep it out of reach of children, avoid direct sunlight, and dispose of any remaining solution after use.

Serious side effects

• Peritonitis
• peritoneal function failure
• respiratory distress
• sepsis
• angioedema

Mild side effects

Abdominal pain, bleeding, peritonitis, inflammation around the abdominal catheter, catheter fracture or drainage difficulties, subcutaneous inflammation, catheter blockage, intestinal obstruction, shoulder pain, nausea, diarrhea, constipation, hemorrhoids, vomiting, loss of appetite, abdominal distension, hypokalemia, hyponatremia, hypocalcemia, hypophosphatemia, hyperlactatemia, hypercalcemia, hypomagnesemia, hypercholesterolemia, hypertriglyceridemia, metabolic acidosis, hypoproteinemia,

This medication should be stored in a sealed container to prevent air ingress, should not be frozen, and should be kept in a cool place below 25 degrees Celsius. Proper storage maintains the drug's efficacy and allows for safe use.

Appearance

A clear, pale yellow transparent peritoneal dialysis solution contained in a colorless transparent plastic bag. 5L/bag (automated peritoneal dialysis) is connected in order of bag connection points and valve wings. 2.5

Package unit

2000 milliliters/bag [2000ml/2 bags], 2500 milliliters/bag [2500ml/2 bags], 2500 milliliters/bag [2500ml/bag], 5000 milliliters/bag [5000ml/bag]