Physioneal 1.5%

Adult administration

Instilled intraperitoneally for dialysis treatment, with a single injection of 2.0–2.5L. In Continuous Ambulatory Peritoneal Dialysis (CAPD), it is performed four times a day (24 hours), while Automated Peritoneal Dialysis (APD) is performed 4-5 cycles overnight and up to 2 times during the day.

This medication is used for peritoneal dialysis treatment and helps in removing waste and excess fluids from the body through the peritoneum. Discontinuing peritoneal dialysis prematurely can pose a threat to life if no other renal replacement therapy is performed, so caution is needed. This medication should not be administered to patients with certain conditions, such as diaphragm defects, abdominal burns, severe peritoneal adhesions, bleeding tendencies, lactate metabolism disorders, severe electrolyte imbalances, recent abdominal surgery or trauma, inflammatory bowel disease, abdominal fistula, intra-abdominal tumors, abdominal hernias, intestinal obstructions, severe respiratory diseases, sepsis, severe lipid metabolism disorders, and patients with difficult uremia control, cachexia, and severe weight loss, as well as patients who cannot comply with medical instructions and those with impaired peritoneal function. Furthermore, it should be used cautiously in patients taking digitalis preparations, suspected of having glucose metabolism disorders, with lumbar disorders, those using an artificial anus, patients on diuretics, those with severe ventilation disorders, severe obesity, steroid users, immune-deficient patients, pregnant women, patients with peritonitis, patients with hyperparathyroidism, those with high lactate levels, and patients with corn allergies, requiring regular monitoring. Adverse reactions such as peritonitis, abdominal pain, electrolyte imbalance, metabolic disorders, respiratory symptoms, endocrine abnormalities, edema, muscle cramps, dehydration, blood pressure abnormalities, skin rash, etc., may appear during administration of this medication, so caution is warranted. During dialysis, maintain a sterile environment, regularly check the patient's weight, nutritional status, and blood test results to manage fluid balance and electrolyte status. Also, this product contains dextrose, so diabetic patients should pay particular attention to blood sugar control, and caution should be taken with patients who have corn allergies due to the risk of hypersensitivity. Overdosage may cause dehydration, electrolyte abnormalities, and hyperglycemia, requiring immediate treatment, and peritoneal dialysis solutions must be handled aseptically and not used if discolored or cloudy or if the container is damaged. Use should be cautious for pregnant women, nursing mothers, children, and the elderly, particularly in children requiring dosage adjustments. During the use of this medication, consider potential interactions with other medications and discuss current medications and conditions with healthcare providers.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in the oral/eye mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and very severe headache, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis, urinary changes

Mild side effects

Abdominal pain, bleeding, peritonitis (abdominal pain, cloudy drainage fluid, sometimes accompanied by fever), inflammation around the abdominal catheter (redness, discharge), subcutaneous inflammation in cases of catheter breakage or drainage difficulty, catheter obstruction, intestinal obstruction, shoulder pain, nausea, diarrhea, constipation, hemorrhoids, vomiting, loss of appetite, abdominal bloating, hypokalemia, hyponatremia, hypocalcemia, hypophosphatemia, hyperlactatemia, hypercalcemia, hypomagnesemia, hypercholesterolemia

This medication should be stored in a sealed container to avoid exposure to air. Additionally, do not freeze the medication and it is important to store it at a cool temperature below 25 degrees.

Appearance

A pale yellow, transparent peritoneal dialysis solution in a colorless, transparent plastic bag. 5L/bag (automated peritoneal dialysis) is connected in the order of the bag connection valve and wings. 2.5L

Package unit

2000 milliliters/bag [2000ml/2 bags], 2500 milliliters/bag [2500ml/2 bags], 2500 milliliters/bag [2500ml/bag], 5000 milliliters/bag [5000ml/bag]