Phenymadol Injection 50 milligrams (Tramadol Hydrochloride)

Adult administration

Inject 50-100mg of tramadol hydrochloride intravenously or intramuscularly, then repeat as needed every 4-5 hours. A maximum of 400mg per day can be administered.

This medication may cause seizures if used above the recommended dose, so the prescribed dosage must be strictly followed. Patients at risk for seizures or those with epilepsy should only use this medication when absolutely necessary, and extra caution is needed when taking other medications that increase the risk of seizures. Prolonged use of this medication may lead to psychological or physical dependence, so patients with a history of drug abuse or dependence should only use it for a short period under strict supervision. Taking this medication with alcohol or central nervous system depressants can lead to severe drowsiness, respiratory depression, coma, or even death, so caution must be exercised when used in combination with such medications. Individuals who metabolize this drug rapidly due to genetic factors may experience unexpectedly stronger effects and risks, requiring careful dosage adjustments and monitoring. It should not be used in children under 12 years old, or in adolescents under 18 years who have undergone tonsillectomy or adenoidectomy, and those between 12 and 18 should also avoid use if they have specific risk factors. It should not be administered to individuals with acute alcohol intoxication, central nervous system drug overdose, severe respiratory depression, head injuries, or those taking MAO inhibitors. Patients with severely impaired liver or kidney function, as well as pregnant or nursing women, should avoid using this medication as it is safer not to do so. Drowsiness and dizziness may occur when using this drug, so driving or operating dangerous machinery should be avoided. Moreover, if this medication is stopped suddenly, withdrawal symptoms may occur, thus the dosage should be reduced gradually as per the doctor's advice. There are many interactions with other drugs; taking it with benzodiazepines, antidepressants, antipsychotics, alcohol, etc., increases the risk of side effects, so one must consult their healthcare provider. During pregnancy or breastfeeding, it should not be used as it may pose risks to the fetus or newborn, especially during breastfeeding as it may transfer to breast milk and cause serious side effects in the baby. In cases of overdose, severe respiratory depression and seizures may occur, and immediate emergency care is needed, with naloxone potentially being used as an antidote. This medication should be kept out of the reach of children and stored in its original container safely.

Serious side effects

Seizures, severe allergic reactions (shock, anaphylaxis, hives, bronchospasm, angioedema), respiratory depression, difficulty breathing, exacerbation of asthma, facial pallor, severe skin reactions (Stevens-Johnson syndrome), severe swelling, liver abnormalities (elevated liver enzyme levels, potential jaundice), serious neurological symptoms (seizures, altered consciousness, fainting), cardiovascular issues (arrhythmias, low blood pressure, high blood pressure, fainting, tachycardia, bradycardia), severe anxiety

Mild side effects

• Drowsiness
• dizziness
• unsteadiness
• nausea
• vomiting
• abdominal pain
• headache
• heaviness in the head
• agitation
• tremors

This medication should be stored in a sealed container to prevent exposure to air and maintained at room temperature between 1 to 30 degrees Celsius for safety. Maintaining appropriate temperature and sealing conditions can prolong the medication's effectiveness.

Appearance

A colorless, transparent solution in an ampoule.

Package unit

1ml/ampoule x 50