Withus Famotidine Tablets 20mg

Adult dosage

For oral administration in the treatment of gastric and duodenal ulcers, anastomotic ulcers, upper gastrointestinal bleeding, gastroesophageal reflux disease, and Zollinger-Ellison syndrome: administer 20 mg twice daily after meals or at bedtime, or 40 mg once daily at bedtime. In cases of upper gastrointestinal bleeding, treatment is started with the injectable form and then switched to oral administration. For improvement of gastric mucosal lesions (acute gastritis, acute exacerbation of chronic gastritis): 10 mg orally, twice daily (after meals or at bedtime) or 20 mg orally, once daily (at bedtime). Adjust according to age and symptoms.

This medication should not be used in patients who have previously shown allergic reactions to its ingredients or other H2 receptor antagonists. Patients with drug hypersensitivity, impaired renal function, heart disease, liver dysfunction, and elderly individuals should exercise special caution when using this drug. Particularly in cases of poor renal function, the drug may remain in the body longer, increasing the risk of side effects; thus, the dosage should be reduced or the administration interval extended. Rarely, this medication may cause serious side effects such as shock, severe allergic reactions, hematological abnormalities, severe skin diseases, hepatic dysfunction, muscle damage, heart rhythm abnormalities, altered consciousness, nephritis, and pneumonia. If any abnormal symptoms appear, the use of the medication should be discontinued immediately, and medical treatment should be sought. Additionally, various mild side effects such as constipation, diarrhea, nausea, vomiting, headache, drowsiness, insomnia, dizziness, and arthralgia may occur, so symptoms should be carefully monitored. During treatment, it is advisable to use the minimum effective dosage while closely observing changes in symptoms, and to switch to alternative treatment if no effect is observed. This medication dissolves in the oral cavity but is not absorbed through the oral mucosa, so it must be swallowed with saliva or water. Patients undergoing hemodialysis should be cautious as the efficacy of calcium supplements may be diminished when this drug is used together with phosphate binders. This medication may reduce the efficacy of certain antifungals or some anticancer agents when taken together; therefore, any other medications being used should be disclosed to the doctor or pharmacist. Elderly patients are more likely to have reduced kidney function, which can increase the blood concentration of this medication; hence, dosage adjustments or extended intervals may be necessary. Women who are pregnant or may become pregnant should use this medication only if the benefits outweigh the risks, as safety has not been fully established. Women who are breastfeeding are advised to discontinue breastfeeding as this medication can pass into breast milk. Safety in children has not been fully established, so caution should be exercised when administering to youngsters. Finally, this medication may mask symptoms of gastric cancer, making diagnosis difficult; therefore, it should only be used after confirming a non-malignant condition.

Serious side effects

Shock, hypersensitivity (anaphylaxis, difficulty breathing, systemic flushing, angioedema (facial swelling, pharyngeal edema, etc.), urticaria), pancytopenia, agranulocytosis, aplastic anemia, hemolytic anemia, thrombocytopenia, Stevens-Johnson syndrome, Lyell syndrome, hepatic dysfunction, jaundice, rhabdomyolysis, QT prolongation, ventricular tachycardia (including Torsades de Pointes), ventricular fibrillation, altered consciousness, seizures, interstitial nephritis, acute renal failure, interstitial pneumonia,

Mild side effects

• Rash
• urticaria (erythema)
• facial swelling
• leukopenia
• eosinophilia
• constipation
• diarrhea
• dry mouth
• nausea
• vomiting

This medication is light-sensitive and should be stored in a container that blocks light. It is also essential to store it at room temperature between 1 to 30 degrees Celsius to maintain its effectiveness.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 500 tablets/bottle