
Key information summary
Efficacy & effects
This medication is used to relieve mild to moderate pain, such as muscle pain, neuralgia, pain after trauma or surgery, headache, toothache, and ear pain.
Dosage
As clonixin lysinate, take 125 to 250 mg orally three times a day.
Precautions
One should consult a doctor or pharmacist before taking this medication if they regularly drink more than three glasses of alcohol daily. This is because taking this medication may increase the risk of gastrointestinal bleeding. This medication may increase the risk of cardiovascular diseases. Particularly, those with cardiovascular diseases or risk factors should be cautious, and if symptoms such as heart attack or stroke occur during use, immediate consultation with healthcare personnel is necessary. This medication can cause serious gastrointestinal issues such as gastrointestinal bleeding, ulcers, and perforations, so patients over the age of 65 or with a history of gastrointestinal disorders should be especially careful. If symptoms of gastrointestinal bleeding or pain occur during use, immediate medical attention should be sought. Patients with peptic ulcers or allergies to this medication or its components, and those with hypersensitivity to aspirin or other non-steroidal anti-inflammatory drugs should not take this medication. Women who are pregnant or may become pregnant, and patients with severe liver dysfunction, kidney dysfunction, or heart failure should also avoid this medication. When taking this medication, it is advised not to use other non-steroidal anti-inflammatory drugs, ACE inhibitors, angiotensin receptor antagonists, aspirin, diuretics, lithium, methotrexate, warfarin, etc. concurrently. Taking these drugs together may increase the risk of side effects, so consultation with a specialist is a must. During treatment, if gastrointestinal symptoms such as nausea, vomiting, abdominal pain, or bloody stools occur, the medication should be stopped immediately and a doctor consulted. Additionally, if symptoms like rash, itching, anemia, liver function abnormalities, drowsiness, or headache occur, healthcare personnel should be informed right away. This medication should be used in the minimum effective dose for the shortest duration possible, and regular blood tests and liver and kidney function tests done during long-term use. Women who are breastfeeding should discontinue nursing or stop taking this medication because it may pass into breast milk.
Side effects
Gastrointestinal bleeding, peptic ulcers and perforations, severe allergic reactions (including hives), shock, cardiovascular thrombotic responses, myocardial infarction, stroke, skin adverse reactions (including Stevens-Johnson syndrome and toxic epidermal necrolysis), respiratory problems (including asthma attacks), liver abnormalities (including jaundice and liver failure), severe neurological symptoms, severe edema or urinary abnormalities
Interactions
Do not take this medication concurrently with non-steroidal anti-inflammatory drugs, ACE inhibitors or angiotensin II receptor antagonists, aspirin, diuretics, lithium, methotrexate, anticoagulants of the coumarin class (such as warfarin), cyclosporine and tacrolimus, antiplatelet agents and selective serotonin reuptake inhibitors (SSRIs), corticosteroids. In cases where misoprostol or similar agents are used for the treatment of peptic ulcers, consult a doctor or specialist.



