Lasix Injection (Furosemide)

Key information summary

Efficacy & effects

This medication is used to improve conditions such as hypertension, edema caused by heart, kidney, or liver diseases, and serious conditions like acute pulmonary edema. It stabilizes blood pressure in both oral and injectable forms and reduces excess fluid accumulation in the body to alleviate symptoms. It is especially effective for edema due to heart failure or kidney issues and also aids in the treatment of acute pulmonary edema. Appropriate dosage forms and dosages will be selected and managed safely according to the patient's condition. This drug is widely used to improve symptoms related to cardiovascular and renal diseases.

Dosage

Oral: Administer 20-80 mg once daily or every other day. If the effect is insufficient, increase by 20-40 mg every 6-8 hours for 1-2 doses per day. In severe cases, up to 600 mg per day is possible. For hypertension, administer 80 mg per day divided into two doses, and if there is insufficient effect, combine with other antihypertensives. Injection: Administer 20-40 mg once daily intravenously or intramuscularly. If there is insufficient effect, administer every 2 hours.

Precautions

This medication is a powerful diuretic that alters the balance of water and electrolytes in the body. Overdosage can lead to severe water and electrolyte deficiencies, so regular tests should be conducted to monitor the condition and adjust the dosage as needed for each patient. Care should be taken when opening the ampule, as there is a risk of glass fragments mixing in, especially when administering to children or the elderly. This medication is contraindicated for certain patients. For instance, it should not be administered to those allergic to this drug or its components, as well as patients with hypovolemia, dehydration, anuria, severe hypokalemia or hyponatremia, severe liver dysfunction, those who are pregnant or breastfeeding, and patients on certain medications. Patients with partial urinary excretion impairment or specific conditions such as hypotension, cardiovascular diseases, diabetes, gout, cirrhosis, or renal impairment should be administered with caution, requiring careful observation and regular testing at the start and during treatment. This drug can cause a variety of side effects. Symptoms such as electrolyte imbalances, reduced blood pressure, impaired kidney function, gastrointestinal disturbances, liver dysfunction, auditory disorders, skin reactions, immune system abnormalities, and neurological symptoms may appear; patients should immediately consult healthcare professionals if symptoms occur. During administration, serum sodium, potassium, and creatinine levels should be regularly monitored, and caution should be taken to prevent dehydration or electrolyte imbalances. Additionally, since the diuretic effect of this drug may occur suddenly, it is safe to start with a low dose and gradually increase. This medication can interact with other drugs, so it is important to exercise caution, especially when taken with certain antibiotics, antipsychotic medications, antihypertensives, lithium preparations, thyroid hormone preparations, etc., and to always consult a physician or pharmacist. During pregnancy, it should not be administered unless under special circumstances as it may affect the fetus, and during breastfeeding, it should also be avoided due to the potential transmission of the drug through breast milk, which may affect the infant. In pediatric patients, particularly preterm infants or neonates, there is a risk of kidney stones or electrolyte imbalances, so careful administration is required, while elderly patients should start with a low dose and be closely monitored. When administering intravenously, it should be injected slowly, with attention paid to potential nerve damage and pain at the injection site. An appropriate solution should be used for dilution, and it should be used as soon as possible after preparation. In case of overdose, severe symptoms may arise due to electrolyte and fluid loss, so it is essential to inform healthcare professionals immediately and receive necessary emergency treatment. There is no antidote, and treatment should focus on symptom relief and electrolyte correction.

Side effects

Urticaria, severe swelling (edema), anaphylactic reaction, anaphylactoid reaction, severe allergy reaction, severe rash with high fever, blistering, skin exfoliation, oral/ocular mucosal pain, Stevens-Johnson syndrome, toxic epidermal necrolysis, similar to pemphigus, acute generalized exanthematous pustulosis, respiratory distress, difficulty breathing, acute urinary retention, renal failure, intrahepatic cholestasis, jaundice, hepatic encephalopathy, altered consciousness, seizures, severe headache, lightning-like pain

Alternatives / Same-ingredient medications

• 

  Hurix Tablets (Furosemide)

  Same ingredient
• Uliracemide (Furosemide)

  Same ingredient

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