Ingredient

Donepezil Hydrochloride Hydrate

Donepezil hydrochloride hydrate is an active ingredient used to improve the symptoms of Alzheimer's-type dementia.

See medicines used for Mental & Nervous System
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294
Single ingredient
286
Combination
8
Prescription medication
294

MFDS ingredient code M256941

What does it do?

Donepezil hydrochloride hydrate is a central nervous system agent used to improve cognitive function in patients with Alzheimer's-type dementia. This ingredient belongs to the class of acetylcholinesterase inhibitors, helping to facilitate nerve signal transmission by slowing the breakdown of neurotransmitters in the brain.

Donepezil hydrochloride hydrate inhibits an enzyme that breaks down the neurotransmitter acetylcholine in the brain. As a result, the concentration of acetylcholine increases, facilitating signal transmission between nerve cells and improving memory and cognitive function.

Commonly used for

Approved uses differ by product. Check each product's information for its actual use.

Good to know

Compared to other acetylcholinesterase inhibitors, donepezil hydrochloride hydrate has a long half-life, allowing for once-daily dosing to maintain efficacy. It also selectively acts on the brain, resulting in relatively fewer side effects.

Medicines containing this ingredient

Even with the same ingredient, strength, dosage form and how it is taken can differ.

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294 total

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Even with the same ingredient, dosage and approved uses can differ by strength, dosage form and combined ingredients. Check each product's information before taking it.

Combined ingredients

Ingredients used together with this ingredient in combination products.

Questions about this ingredient

  • QMy grandmother is taking donepezil for dementia; what kind of medication is that?

    Donepezil hydrochloride hydrate is an acetylcholinesterase inhibitor used to improve symptoms of Alzheimer's-type dementia. It helps facilitate signal transmission between nerve cells by inhibiting the enzyme that breaks down acetylcholine in the brain, aiming to improve cognitive function. Please follow the guidance of your prescribing doctor regarding the timing and method of administration.

    Answers 1 · 2026.09.14

For anything that needs medical judgment, consult a doctor or pharmacist.

SourceKorea Ministry of Food and Drug Safety (Drug Safety Korea)

This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.