Y.S. Alpha Tablet 0.5 Micrograms (Alfacalcidol)

Adult dosage

Chronic renal failure and osteoporosis: Administer 0.5 to 1 µg orally once daily as alfacalcidol. Hypoparathyroidism and other diseases due to vitamin D metabolism disorders: Administer 1 to 4 µg orally once daily.

Children's dosage

Osteoporosis: Administer 0.01 to 0.03 µg per kg of body weight orally once daily as alfacalcidol. Other conditions: Administer 0.05 to 0.1 µg per kg of body weight orally once daily.

This drug should not be used in patients with hypercalcemia, hyperphosphatemia, or hypermagnesemia. It should also be avoided if the product of calcium and phosphorus in the blood exceeds a certain level. Patients who have alkalosis or symptoms of vitamin D toxicity should not use this drug either. If there is an allergy to any components of this drug or vitamin D analogs, it should be avoided. It contains lactose, so patients with hereditary lactose intolerance or related conditions should exercise caution. While taking this medication, the risk of side effects increases if taken with magnesium-containing drugs, vitamin D preparations, calcium supplements, or certain diuretics, therefore, they should not be taken together. It is advisable to avoid breastfeeding while taking this medication, and if unavoidable, it is preferable to discontinue breastfeeding. Women who are pregnant or may become pregnant should consult with a doctor before taking this medication as it may be harmful to the fetus. Dosing may need to be adjusted and caution is necessary for children and the elderly due to physiological differences. Patients on certain medications should consult with a professional due to the possibility of drug interactions. Patients with kidney stones or sarcoidosis should always consult with a doctor before taking this medication. During the use of this medication, various symptoms associated with hypercalcemia may occur, such as digestive disturbances, neurological abnormalities, heart problems, decreased kidney function, liver dysfunction, skin rashes, eye problems, and bone pain. If such symptoms occur, stop taking the medication immediately and consult a professional. Regularly check serum calcium and phosphorus levels to maintain them within normal ranges, and in cases of hyperphosphatemia, dietary phosphorus restriction and phosphate binders may be necessary. In case of overdose, stop taking the medication immediately and seek appropriate treatment, including possible emergency measures such as inducing vomiting or gastric lavage. This medication should be kept out of reach of children and stored in a cool, dry place, away from direct sunlight. Do not transfer to another container to prevent misuse or abuse.

Serious side effects

• Urticaria, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions
• Severe rash, blisters, skin peeling, pain in oral/ocular mucosa accompanied by high fever, severe skin adverse reactions
• Difficulty breathing or oppression, asthma attacks, respiratory disturbances with cough and fever, respiratory problems
• Yellowing of skin or eyes (jaundice), extreme lethargy, liver problems (jaundice)
• Sudden and severe headache

Mild side effects

• Loss of appetite
• nausea
• vomiting
• diarrhea
• constipation
• stomach pain
• discomfort in the upper abdomen
• abdominal bloating
• indigestion
• thirst

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is advisable to maintain a storage temperature between 1 to 30 degrees Celsius.

Appearance

White round tablet

Package unit

Bottle - 30 tablets/bottle, Bottle - 100 tablets/bottle