Telmitrip tablet 40/5/12.5 milligrams (Telmisartan, Amlodipine, Chlorthalidone)

Adult dose

Take 1 tablet once daily, regardless of meals, with water. It is recommended to take it at the same time every day (e.g., in the morning). This medication can be administered to patients whose blood pressure is not controlled with telmisartan/amlodipine combination therapy at a dosage of 40/5/12.5 mg, and the dosage may be adjusted after two weeks, considering the patient's blood pressure response. The maximum dosage of this medication is 80/5/25 mg.

This medication should not be used during pregnancy, especially in the second and third trimesters, as it can cause serious harm to the fetus. If pregnancy is confirmed, treatment should be discontinued immediately, and other safe treatment options should be considered. Patients with impaired liver function or progressing liver disease should exercise caution, as serious side effects such as hepatic encephalopathy may occur when taking this medication. Patients with severe renal disease may experience elevated blood nitrogen levels due to certain components of this medication, hence kidney function should be closely monitored. Patients with a history of allergy or hypersensitivity to this medication or its components should not use it. Breastfeeding women should also refrain from taking this medication, and it is recommended to discontinue nursing. Specific patients with severe liver disease, obstructive biliary conditions, severe aortic stenosis, or in shock should avoid this medication. Patients with excessively low blood pressure or severe renal failure, as well as those experiencing hypokalemia, hyponatremia, or hypercalcemia should use this medication with care. Since this medication lowers blood pressure, dizziness or orthostatic hypotension may occur initially, requiring caution. The elderly or dehydrated patients are at greater risk of hypotension, hence dosage adjustments may be necessary. During treatment with this medication, regular blood tests for potassium, sodium, creatinine, and kidney function should be conducted. This medication can interact with other antihypertensives, diuretics, lithium, digoxin, warfarin, and non-steroidal anti-inflammatory drugs. Therefore, if there are other medications being taken, it is essential to inform a physician or pharmacist. In the case of overdose, symptoms such as hypotension, dizziness, and cardiac irregularities may occur, requiring immediate medical attention. This medication is not recommended for children, as its safety and efficacy have not been established. When storing, keep in a cool, dry place out of reach of children, and avoid direct sunlight.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, peeling skin, pain in mucous membranes of the mouth/eyes, difficulty breathing or shortness of breath, asthma attacks, respiratory abnormalities with cough and fever, yellowing of the skin or eyes (jaundice), extreme malaise, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

• Dizziness
• headache
• insomnia
• reduced perception
• abdominal pain
• rectal bleeding
• nausea
• hemorrhagic gastritis
• constipation
• retinal hemorrhage

This medication is sensitive to light and should be stored in a tightly closed container that blocks light. It is important to maintain a storage temperature between 1 to 30 degrees Celsius.

Appearance

White oval biconvex tablet

Package unit

30 tablets/box (6 tablets/PTP*5)