Twinklelo Tablet 80/5/12.5 mg (Telmisartan, Amlodipine, Chlorthalidone)

Adult dose

This medication is taken once daily with water, regardless of meals. It is recommended to take it at the same time every day (e.g., in the morning). Patients whose blood pressure is not controlled with a combination therapy of telmisartan/amlodipine may be prescribed this medication at 40/5/12.5 mg, and the dosage may be adjusted considering the patient's blood pressure response at intervals of more than 2 weeks. The maximum dosage of this medication is 80/5/25 mg.

This medication can cause serious harm to the fetus during pregnancy, especially in the second and third trimesters, so it should not be used by women who are pregnant or may become pregnant. Patients with impaired liver function or progressive liver disease should be cautious when using this medication, as serious side effects such as hepatic coma may occur. Patients with severe kidney disease may experience increased blood urea nitrogen levels due to certain components of this medication, and the drug may accumulate in the body, increasing the risk of side effects. Individuals allergic to any of the ingredients of this medication or who have had hypersensitivity reactions should not take it. Administration is prohibited in patients with certain conditions such as pregnant women, nursing mothers, patients with biliary obstruction disease, severe liver impairment, severe aortic stenosis, and those in shock. Patients with diabetes or moderate to severe kidney impairment should not take this medication with drugs containing aliskiren. This medication should be used cautiously in the elderly, especially to avoid symptoms of low blood pressure, electrolyte imbalances, and dehydration. Due to its blood pressure lowering effects, dizziness or orthostatic hypotension may occur, so patients should be careful with sudden changes in posture while taking it, and consult healthcare professionals if necessary. During the use of this medication, it's important to regularly check electrolyte levels and kidney function through blood tests. Interactions may occur when this medication is taken with other drugs, so patients must inform healthcare providers of any other medications they are taking. This medication should not be administered to nursing women, and if breastfeeding is necessary, alternative treatments should be considered. In case of overdose, symptoms such as low blood pressure, dizziness, and in severe cases, shock may occur, so immediate medical attention is required. This medication is not recommended for use in children as safety and efficacy have not been established.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, paleness, severe rash with high fever, blisters, skin peeling, pain in mouth/eye membranes, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), profound lethargy, sudden and severe headache, lightning headaches, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

• Dizziness
• dyslipidemia
• back pain
• rash
• abdominal pain
• rectal bleeding
• nausea
• hemorrhagic gastritis
• constipation
• retinal hemorrhage

This medication should be stored in a dark place because it is sensitive to light, and it should be kept in a tightly closed container that is well-ventilated. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius, at room temperature.

Appearance

White oval-shaped bilayer tablet

Package unit

30 tablets/box [(10 tablets/PTP*3)]