Bonem 10mg Tablet (Bonooprazan HCl)

Adult dose

○ Treatment of gastric ulcer Adults: Administer vonoprazan 20mg orally once daily. Treatment is usually given for up to 8 weeks. ○ Treatment of erosive gastroesophageal reflux disease and maintenance therapy after treatment Treatment: Adults: Administer vonoprazan 20 mg orally once daily. Treatment is usually given for up to 4 weeks. If the effect is insufficient, treatment may be continued for up to 8 weeks. Maintenance therapy: Administer 10 mg orally once daily. If the effect is insufficient, 20 mg may be administered orally once daily. ○ Prevention of recurrence of gastric or duodenal ulcers during administration of nonsteroidal anti-inflammatory drugs (NSAIDs) Adults: Administer vonoprazan 10mg orally once daily.

This drug should not be used by patients who are allergic to this drug or its components or have a history of hypersensitivity. Furthermore, it is contraindicated for patients taking certain antiviral medications like Atazanavir, Nelfinavir, or Rilpivirine. Caution should be exercised when administering this drug to patients with impaired renal function, liver function issues, and the elderly. Various gastrointestinal symptoms such as abdominal pain, constipation, diarrhea, nausea, and vomiting may occur when taking this drug, and rarely, abnormalities such as gastritis or gastric polyps may also occur. Additionally, side effects including edema, allergic reactions, infections, myalgia, dizziness, insomnia, and skin rashes have been reported. Since liver function abnormalities and hepatotoxicity may occur, immediate discontinuation of this drug is necessary if symptoms of liver dysfunction arise. It is important to periodically monitor the condition through endoscopic examinations during long-term use. While this drug reduces gastric acid and aids in the treatment of gastrointestinal diseases, care must be taken as it may conceal symptoms of gastric cancer or increase the risk of recurrent gastric ulcers. Particularly, in older adults or with prolonged high-dose administration, the risk of fractures associated with osteoporosis may increase. This drug alters gastric acidity and can affect the absorption of other medications, so it should not be combined with certain drugs, and consultation with a specialist is necessary when taken together. Women who are pregnant or potentially pregnant should avoid this drug unless in special circumstances. If breastfeeding, it is advisable to avoid breastfeeding during treatment as this drug may be passed into breast milk. Safety for children has not been adequately established, so caution is advised when administering to children. In the elderly, metabolism of the drug may slow down due to decreased renal and liver function, so caution is warranted during administration.

Upper abdominal pain, constipation, dental caries, diarrhea, gastric polyps, gastritis, nausea, stomatitis, vomiting, peripheral edema, seasonal allergies, bronchitis, gastroenteritis, influenza, nasopharyngitis, esophageal candidiasis, periodontitis, pharyngitis, sinusitis, contusion, fall, ligament sprain, procedure-related bleeding, increase in alanine aminotransferase, increase in blood creatine phosphokinase, increase in blood triglycerides, increase in blood uric acid, increase in gamma-glutamyltransferase, arthralgia, low back pain, osteoarthritis, periradiculitis, dizziness, insomnia, allergic rhinitis, upper respiratory tract inflammation, contact dermatitis, eczema, anemia, iron deficiency anemia, aortic valve dysfunction, atrial fibrillation, right bundle branch block, vertigo, subacute thyroiditis, corneal exfoliation, dry eyes, eyelid eczema, open-angle glaucoma, abdominal discomfort, abdominal distension, lower abdominal pain, abdominal pain, irregular bowel movement, appendicitis, cheilitis, duodenal polyps, small intestine colitis, discomfort in the upper abdomen, stool discoloration, bloating, functional gastrointestinal disorder, gastric hemorrhage, gastric mucosal lesion, erosive gastritis, hemorrhagic gastritis, abnormal gastric sounds, gastroesophageal reflux disease, glossitis, hemorrhoids, oral sensory loss, intestinal obstruction, colon polyps, lip erosion, salivary gland pain, chest pain, facial edema, malaise, edema, polyp, fever, thirst, drug-induced liver injury, abnormal liver function, otitis media, pneumonia, subcutaneous abscess, facial tinea, muscle injury, increase in aspartate aminotransferase, increase in eosinophils, increase in alkaline phosphatase in blood, increase in blood bilirubin, increase in blood cholesterol, decrease in blood iron, increase in blood iron, increase in blood lactate dehydrogenase, increase in blood magnesium, increase in blood potassium, increase in blood urea, presence of hematuria, increase in eosinophils, presence of glucosuria, increase in liver enzymes, abnormal liver function tests, decrease in lymphocytes, decrease in neutrophils, increase in neutrophils, presence of protein in urine, abnormal kidney function tests, increase in vitamin B12, decrease in white blood cell count, increase in white blood cell count, diabetes, gout, hypertriglyceridemia, hyperuricemia, type 2 diabetes, muscle weakness, cervical pain, polyarthritis, rotator cuff syndrome, bladder cancer, gastric adenoma, malignant fibrous histiocytoma, malignant neoplasm of the renal pelvis, headache, sensory loss, peripheral neuropathy, cochlear bleeding, drowsiness, ureteral stone, frequent urination, asthma, laryngeal pain, discomfort in the oropharynx, vascular edema, dermatitis, erythema, petechial hemorrhage, itchy rash, pruritus, generalized rash, rash, urticaria, blue toe syndrome, hypertension, drug hypersensitivity, urticaria, drug eruption, pancytopenia, agranulocytosis, leukopenia, thrombocytopenia, hepatotoxicity, jaundice, rash, polymorphic erythema, Stevens-Johnson syndrome, toxic epidermal necrolysis

This drug is sensitive to light, so it should be stored in a tightly sealed container that blocks light. Additionally, it should be stored at room temperature between 1 degree and 30 degrees Celsius. This way, the effectiveness of the drug can be safely maintained.

Appearance

Pale yellow oval film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle