Bonoem Tablet 20mg (Bonoabasan Tosylate)

Adult dose

Treatment of gastric ulcer: Adults: Administer vonoprazan 20mg orally once daily. Treatment is usually given for up to 8 weeks. Treatment of erosive gastroesophageal reflux disease and maintenance therapy after treatment Treatment: Adults: Administer vonoprazan 20 mg orally once daily. Treatment is usually given for up to 4 weeks. If the effect is insufficient, treatment may be continued for up to 8 weeks. Maintenance therapy: Administer 10 mg orally once daily. If the effect is insufficient, 20 mg may be administered orally once daily. Prevention of recurrence of gastric or duodenal ulcers during administration of nonsteroidal anti-inflammatory drugs (NSAIDs): Adults: Administer vonoprazan 10mg orally once daily.

This medication should not be administered to patients with hypersensitivity to this drug or its components, or with a history of such reactions. Moreover, it is recommended not to use this drug concurrently in patients taking specific antivirals such as atazanavir, nelfinavir, or rilpivirine. Caution should be exercised when using this drug in patients with impaired renal function, liver issues, and in elderly patients. While taking this medicine, gastrointestinal disorders such as epigastric pain, constipation, diarrhea, nausea, and vomiting may occur. Additionally, abnormal reactions such as peripheral edema, allergic reactions, symptoms of infection, musculoskeletal pain, dizziness, and insomnia have also been reported. Liver function abnormalities or hepatotoxicity may occur; therefore, if there are any abnormal liver function test results or symptoms indicating deteriorating liver function, use must be immediately discontinued. For long-term use, regular monitoring such as endoscopy is necessary as it can mask serious conditions such as gastric cancer. When using this drug to prevent the recurrence of gastric or duodenal ulcers in patients who have taken NSAIDs for a long time, a history of gastric ulcer must be confirmed. This medication may increase the risk of osteoporosis-related fractures; thus, caution is particularly necessary for elderly patients or those at high risk of fractures. Additionally, this medication can lower gastric acidity, which may impair the absorption of certain drugs, so it is important not to combine it with drugs like atazanavir, nelfinavir, and rilpivirine. Occasionally, this medication may affect the metabolism of other drugs, therefore if other medications are being taken, it is essential to consult a doctor or pharmacist. Women who are pregnant or may become pregnant should refrain from taking this medication unless in specific circumstances, and breastfeeding women are recommended to discontinue breastfeeding during the use of this medication. Safety in pediatrics has not been sufficiently established; hence it should be used cautiously in children. Finally, elderly individuals may be more affected due to decreased liver and kidney function, requiring special caution while taking this medication.

Abdominal pain, constipation, cavities, diarrhea, gastric polyps, gastritis, nausea, stomatitis, vomiting, peripheral edema, seasonal allergies, bronchitis, gastroenteritis, influenza, nasopharyngitis, esophageal candidiasis, periodontitis, pharyngitis, sinusitis, contusions, falls, ligament sprains, procedure-related bleeding, increased alanine aminotransferase, increased creatine phosphokinase in blood, increased triglycerides in blood, increased uric acid in blood, increased gamma-glutamyltransferase, arthralgia, low back pain, osteoarthritis, periarthritis, dizziness, insomnia, allergic rhinitis, upper respiratory tract inflammation, contact dermatitis, eczema, anemia, iron deficiency anemia, aortic valve dysfunction, atrial fibrillation, right bundle branch block, vertigo, subacute thyroiditis, corneal detachment, dry eyes, eyelid eczema, open-angle glaucoma, abdominal discomfort, abdominal distension, lower abdominal pain, abdominal pain, irregular bowel movements, appendicitis, cheilitis, duodenal polyps, small bowel colitis, discomfort in the upper abdomen, stool discoloration, bloating, functional gastrointestinal disorder, gastric bleeding, gastric mucosal lesion, erosive gastritis, hemorrhagic gastritis, abnormal gastric sounds, gastroesophageal reflux disease, glossitis, hemorrhoids, oral sensory decrease, intestinal obstruction, colorectal polyps, lip erosion, salivary gland pain, chest pain, facial edema, malaise, edema, polyps, fever, thirst, drug-induced liver injury, liver function abnormality, otitis media, pneumonia, subcutaneous abscess, facial tinea, muscle injury, increased aspartate aminotransferase, increased eosinophil count, increased alkaline phosphatase in blood, increased bilirubin in blood, increased cholesterol in blood, decreased iron in blood, increased iron in blood, increased lactate dehydrogenase in blood, increased magnesium in blood, increased potassium in blood, increased urea in blood, presence of hematuria, increased eosinophils, presence of glucose in urine, increased liver enzymes, abnormal liver function tests, decreased lymphocyte count, decreased neutrophil count, increased neutrophil count, presence of protein in urine, abnormal renal function tests, increased vitamin B12, decreased white blood cell count, increased white blood cell count, diabetes, gout, hypertriglyceridemia, hyperuricemia, type 2 diabetes, muscle weakness, cervical pain, polyarthritis, rotator cuff syndrome, bladder cancer, gastric adenoma, malignant fibrous histiocytoma, malignant neoplasm of the renal pelvis, headache, sensory decrease, peripheral neuropathy, cochlear hemorrhage, drowsiness, ureteral stones, frequent urination, asthma, laryngeal pain, oropharyngeal discomfort, vascular edema, dermatitis, erythema, petechiae, itchy rash, pruritus, systemic rash, rash, urticaria, blue toe syndrome, hypertension, drug hypersensitivity, urticaria, drug rash, pancytopenia, agranulocytosis, leukopenia, thrombocytopenia, hepatotoxicity, jaundice, rash, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis

This medicine is sensitive to light and should be stored in a tightly closed container that blocks light. It is essential to maintain the storage temperature between 1 to 30 degrees Celsius to ensure the medication's efficacy and safety.

Appearance

Pale pink oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle