Medication info

Duractosyrup (Lactulose Concentrate)

OTC medicationSyrup경구
Ingredient · strength
Lactulose Concentrate Solution›134g / 100mL
Manufacturer / importer
(주)테라젠이텍스
Appearance
A viscous syrup in a colorless to light yellow hue, contained in an aluminum foil pouch.
Packaging
15 milliliters per pouch, 20 pouches per box
Approval status
Active

MFDS item code 202600042 · Notified 2026.01.06

Summary

Main use
Improvement of chronic constipation and constipation in infants and young children
Who takes it
Adults · Children
Adult dose
For chronic constipation, take before breakfast. Adults should take 15 to 30 mL by mouth before breakfast for the first 2 to 3 days, followed by 10 to 15 mL once daily. In severe cases, a dosage of up to 45 mL may be taken.
Child dose
For children (ages 7 to 14), administer 15 mL once daily for the first 2 to 3 days, followed by 10 mL once daily. For infants (ages 1 to 6), administer 5 to 10 mL once daily. For babies (under 12 months), administer 5 mL once daily.

Ingredients

Manufacturer
(주)테라젠이텍스

Efficacy & effects

Improvement of chronic constipation and constipation in infants and young children

  • Chronic constipation
  • constipation in infants and young children
  • constipation after childbirth
View approved original text

This medication is used to treat constipation, chronic constipation, and constipation in infants and children. It is also effective in alleviating symptoms of constipation that occur after childbirth. It is used to improve various forms of constipation.

How to take

Adult dose

For chronic constipation, take before breakfast. Adults should take 15 to 30 mL by mouth before breakfast for the first 2 to 3 days, followed by 10 to 15 mL once daily. In severe cases, a dosage of up to 45 mL may be taken.

Child dose

For children (ages 7 to 14), administer 15 mL once daily for the first 2 to 3 days, followed by 10 mL once daily. For infants (ages 1 to 6), administer 5 to 10 mL once daily. For babies (under 12 months), administer 5 mL once daily.

Precautions

This medication should not be taken by patients with inflammatory bowel disease, intestinal obstruction, unexplained abdominal pain, patients requiring a low-galactose diet, patients at risk of gastrointestinal perforation, and individuals allergic to this medication or any of its ingredients. Additionally, as it contains lactose, patients with genetic issues such as galactose intolerance, lactase deficiency, and glucose-galactose malabsorption should avoid taking it. Pregnant or potentially pregnant women, nursing mothers, infants and young children, the elderly, diabetic patients, patients with fructose intolerance, patients with fluid and electrolyte imbalance, patients with acute gastritis, and chronic constipation patients should consult their doctor or pharmacist before taking this medication. It is particularly important for the elderly to regularly check electrolyte levels in the blood during prolonged use. This medication may interact with certain drugs, so patients taking drugs such as acarbose (an α-glucosidase inhibitor), broad-spectrum antibiotics, diuretics, corticosteroids, amphotericin B, cardiac glycosides, and antacids should consult a doctor. If constipation does not improve after more than one week of taking this medication or if there are sudden changes in bowel habits, treatment should be stopped immediately, and a healthcare professional should be consulted. In case of overdose, abdominal cramps, diarrhea, and electrolyte loss may occur, so it is essential to stop taking the medication immediately and follow a doctor's instructions when any unusual symptoms appear. Prolonged or excessive use may lead to dependence of the bowel reflex on the drug, so caution is needed, and if loose stools or diarrhea occur, the dosage should be reduced or discontinued. Gastrointestinal side effects may include belching, abdominal cramps, diarrhea, abdominal distension, abdominal pain, loss of appetite, nausea, vomiting, electrolyte loss, hypokalemia, hypernatremia, and potential for dental caries. Patients taking this medication should ensure thorough bowel cleansing before undergoing rectal examinations or colonoscopies, as there may be a risk of explosion due to high concentrations of hydrogen gas in the intestines. Prolonged or excessive use may lead to fluid loss and electrolyte disturbances, so caution is required, and for prolonged administration in children, attention must be paid to oral hygiene due to the increased risk of cavities. Pregnant or nursing women should always consult healthcare professionals before taking this medication. This medication should be kept out of the reach of children and stored securely in its original container, tightly closed.

Side effects and when to seek care immediately

Mild side effects

  • Belching
  • crampy abdominal discomfort
  • diarrhea
  • abdominal pain
  • abdominal distension
  • abdominal pain
  • loss of appetite
  • nausea
  • vomiting
  • electrolyte loss
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  • hypokalemia
  • hypernatremia
  • potential for dental caries

Not everyone experiences these, and they can vary from person to person.

Storage

This medication must be stored in a tightly sealed container to protect it from air or moisture. It is recommended to maintain a storage temperature between 1 and 30 degrees Celsius.

Appearance and packaging

Appearance

A viscous syrup in a colorless to light yellow hue, contained in an aluminum foil pouch.

Package unit

15 milliliters per pouch, 20 pouches per box

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.