Medication info

Melabri Cream (Hydroquinone)

OTC medicationCream피부
Ingredient · strength
Hydroquinone›40mg / 1g
Manufacturer / importer
(주)유한양행
Appearance
White cream preparation
Packaging
30 grams/tube
Approval status
Active

MFDS item code 202503383 · Notified 2025.12.24

Summary

Main use
Gradual whitening effect on excessive pigmentation (lentigines, melasma, etc.)
Who uses it
Adults
Adult use
Hydroquinone 2% or 4%, applied once or twice daily (morning, before bedtime) to the affected area.

Ingredients

Manufacturer
(주)유한양행

Efficacy & effects

Gradual whitening effect on excessive pigmentation (lentigines, melasma, etc.)

  • Excessive pigmentation
  • lentigines
  • melasma
  • freckles
  • senile lentigines
  • excessive melanin pigmentation
View approved original text

This medication is used to gradually improve symptoms of excessive melanin pigmentation that darkens the skin, such as lentigines, melasma, freckles, and senile lentigines. It also helps to gradually whiten excessive pigmentation on unwanted areas, evening out skin tone. In other words, it is effective in alleviating excessive pigmentation of the skin and improving the patient's skin condition.

How to apply

Adult use

Hydroquinone 2% or 4%, applied once or twice daily (morning, before bedtime) to the affected area.

Precautions

This medication may cause discoloration of the skin when exposed to sunlight, so it is essential to apply sunscreen or wear protective clothing while using it. It is advisable not to use this medication for an extended period, and the duration of use should be adjusted based on the treatment effect. Animal studies have indicated that the ingredients in this medication may be carcinogenic, so caution is needed. Individuals with allergies to this medication or its components, or those with a history of hypersensitivity, should not use it. Women who are pregnant or may become pregnant, children under 12 years of age, and individuals with kidney impairment should also avoid using this medication. This medication contains ingredients that may cause allergic reactions, so those with asthma or allergic constitutions should be particularly careful. If any reactions such as itching, blisters, or severe inflammation occur on the skin during use, immediately discontinue use and consult a doctor or pharmacist. When using for the first time, apply a small amount to the skin and observe for reactions for 24 hours. Mild redness is acceptable, but if itching or severe inflammation occurs, it should not be used. If symptoms do not improve after using the medication for about 2 months, it is advisable to discontinue use. This medication should be used solely for skin depigmentation purposes and is not suitable for sun protection or sunburn prevention. Women who are pregnant or breastfeeding should avoid using this medication or use it cautiously after consulting a physician. The safety and efficacy of this medication have not been confirmed in children under 12 years of age, so it is not to be used in this population. Excessive use may cause redness or a sensation of heat on the skin, so application should not be excessive and should be limited to 10% of the total skin area. This medication is for external use only and should be kept away from the eyes or mucous membranes. Keep out of reach of children and do not transfer to other containers. Long-term use (over approximately 8 years) may lead to adverse reactions in the skin, so it is safer to avoid prolonged use.

Side effects and when to seek care immediately

Serious side effects

Severe allergic reactions such as anaphylaxis, asthma attacks

Mild side effects

  • Skin discoloration
  • contact dermatitis
  • skin hypersensitivity
  • redness
  • itching
  • blisters
  • excessive inflammation
  • temporary skin erythema
  • mild burning sensation

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a container that can block light and air. Additionally, it is essential to keep it in a cool, dry place below 30 degrees Celsius. Proper storage will help maintain the medication's efficacy and safety over a longer period.

Appearance and packaging

Appearance

White cream preparation

Package unit

30 grams/tube

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.