Question 1

What are the indications and effects of Boshin-T Tablet 10 mg (Vonoprazan Fumarate)?

Accepted Answer

This medicine is effective in treating gastric ulcers and erosive gastroesophageal reflux disease. In addition, it is used for maintenance therapy to prevent recurrence after treatment for erosive gastroesophageal reflux disease. Furthermore, it helps prevent the recurrence of gastric ulcers or duodenal ulcers that may occur during the use of non-steroidal anti-inflammatory drugs (NSAIDs). It is used to protect the patient's gastric health and improve symptoms.

Question 2

What are the dosage and administration instructions for Boshin-T Tablet 10 mg (Vonoprazan Fumarate)?

Accepted Answer

● Treatment of gastric ulcers
Administer 20 mg of vonoprazan orally once daily to adults. Treatment is generally given for up to 8 weeks.
● Treatment of erosive gastroesophageal reflux disease and maintenance therapy after treatment
Treatment: Administer 20 mg of vonoprazan orally once daily to adults. Treatment is generally given for up to 4 weeks. If the effect is insufficient, treatment may be continued for up to 8 weeks.
Maintenance therapy: Administer 10 mg once daily. If the effect is insufficient, 20 mg may be administered once daily.
● Prevention of recurrence of gastric or duodenal ulcers during administration of nonsteroidal anti-inflammatory drugs (NSAIDs)
Administer 10 mg of vonoprazan orally once daily to adults.

Question 3

What are the side effects of Boshin-T Tablet 10 mg (Vonoprazan Fumarate)?

Accepted Answer

Upper abdominal pain, constipation, dental caries, diarrhea, gastric polyps, gastritis, nausea, stomatitis, vomiting, peripheral edema, seasonal allergy, bronchitis, gastroenteritis, influenza, nasopharyngitis, esophageal candidiasis, periodontitis, pharyngitis, sinusitis, contusion, fall, ligament sprain, procedure-related bleeding, increased alanine aminotransferase, increased blood creatine phosphokinase, increased blood triglycerides, increased blood uric acid, increased γ-glutamyltransferase, arthralgia, back pain, osteoarthritis, periarthritis, dizziness, insomnia, allergic rhinitis, upper respiratory inflammation, contact dermatitis, eczema, anemia, iron deficiency anemia, aortic valve dysfunction, atrial fibrillation, right bundle branch block, vertigo, subacute thyroiditis, corneal desquamation, dry eyes, eyelid eczema, open-angle glaucoma, abdominal discomfort, abdominal distension, lower abdominal pain, abdominal pain, irregular bowel movements, appendicitis, cheilitis, duodenal polyps, small intestinal colitis, discomfort in the upper abdomen, stool discoloration, bloating, functional gastrointestinal disorder, gastric bleeding, gastric mucosal lesions, erosive gastritis, hemorrhagic gastritis, abnormal gastric sounds, gastroesophageal reflux disease, glossitis, hemorrhoids, oral sensory impairment, intestinal obstruction, colon polyps, lip erosion, salivary gland pain, chest pain, facial edema, malaise, edema, polyp, fever, thirst, drug-induced liver injury, abnormal liver function, otitis media, pneumonia, subcutaneous abscess, facial tinea, muscle injury, increased aspartate aminotransferase, increased eosinophil count, increased blood alkaline phosphatase, increased blood bilirubin, increased blood cholesterol, decreased blood iron, increased blood iron, increased blood lactate dehydrogenase, increased blood magnesium, increased blood potassium, increased blood urea, presence of hematuria, increased eosinophil count, presence of glucosuria, increased liver enzymes, abnormal liver function tests, decreased lymphocyte count, decreased neutrophil count, increased neutrophil count, presence of proteinuria, abnormal kidney function tests, increased vitamin B12, decreased white blood cell count, increased white blood cell count, diabetes mellitus, gout, hypertriglyceridemia, hyperuricemia, type 2 diabetes mellitus, muscle weakness, cervical pain, polyarthritis, rotator cuff syndrome, bladder cancer, gastric adenoma, malignant fibrous histiocytoma, malignant neoplasm of the renal pelvis, headache, sensory impairment, peripheral neuropathy, cochlear bleeding, drowsiness, ureteral stones, frequent urination, asthma, laryngeal pain, oropharyngeal discomfort, vascular edema, dermatitis, erythema, petechiae, itchy rash, pruritus, generalized rash, rash, urticaria, cyanotic toe syndrome, hypertension, drug hypersensitivity, urticaria, drug rash, pancytopenia, agranulocytosis, leukopenia, thrombocytopenia, hepatic toxicity, jaundice, rash, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis

Question 4

What precautions should be taken when using Boshin-T Tablet 10 mg (Vonoprazan Fumarate)?

Accepted Answer

This medicine should not be used by patients who have had an allergic reaction to this medicine or its components.
Additionally, if taken with certain antiviral medications, the effectiveness of the drug may be reduced, so co-administration should be avoided.
Care should be taken when using this medicine in patients with poor kidney or liver function, as well as in the elderly.
While taking this medicine, symptoms such as abdominal pain, constipation, diarrhea, and nausea may occur, so caution is needed.
Liver dysfunction may occur, so if there are changes in liver function test results or symptoms, consult a healthcare professional immediately.
Regular examinations such as endoscopy may be required for long-term use, and the potential for masking symptoms of gastric cancer should be verified before administration.
In particular, caution should be exercised in the elderly or patients taking high doses for a long time, as the risk of fractures may be increased.
This medicine reduces gastric acidity and may affect the absorption of other medications, so it is important to inform healthcare professionals about any concomitant medications.
Pregnant women or those who may become pregnant are advised to avoid using this medicine unless there are special circumstances.
Breastfeeding mothers should avoid breastfeeding during treatment, as this medicine may be excreted in breast milk.
Safety in children has not been established, so it should not be used in children as a principle.
When taking the medication, the packaged tablet should be taken out for administration, and care should be taken not to swallow the packaging.
By adhering to these precautions, this medicine can be used more safely.

Boshin-T Tablet 10 mg (Vonoprazan Fumarate)

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Efficacy & effects

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Adult dose

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