Medication info
Amlokande Tablet 16/5 mg (Candesartan Cilexetil, S-Amlodipine Besilate)

Amlokande Tablet 16/5 mg (Candesartan Cilexetil, S-Amlodipine Besilate)

Prescription medicationTablet경구
Ingredient · strength
Candesartan Cilexetil›16mg / 1 tabletS-Amlodipine Besylate 2.5 Hydrate›7.48mg / 1 tablet
Manufacturer / importer
알리코제약(주)
Appearance
White, double convex, round film-coated tablet
Packaging
30 tablets/bottle
Approval status
Active

MFDS item code 202503324 · Approved 2025.12.19

Summary

Main use
Improvement in blood pressure control for essential hypertension
Who takes it
Adults · Children
Adult dose
The recommended dosage of this medication is 1 tablet once daily, taken with water regardless of meals. It is preferable to take it at the same time every day (e.g., in the morning). For patients with renal impairment, an initial dose of 4 mg once daily of candesartan cilexetil is recommended, making this medication unsuitable for initial treatment. For patients with hepatic impairment, an initial dose of 2 mg once daily of candesartan cilexetil is recommended.
Child dose
The safety and efficacy of this medication in adolescents and children under 18 years of age have not been established, and its use is not recommended.

Ingredients

Manufacturer
알리코제약(주)

Efficacy & effects

Improvement in blood pressure control for essential hypertension

  • Essential hypertension
View approved original text

This medication is used to effectively lower blood pressure in patients with essential hypertension whose blood pressure is not adequately controlled by monotherapy with candesartan cilexetil or S-amlodipine. This helps to stabilize blood pressure and reduce the risk of complications due to hypertension. Such treatment aids in improving cardiovascular health and enhancing overall quality of life.

How to take

Adult dose

The recommended dosage of this medication is 1 tablet once daily, taken with water regardless of meals. It is preferable to take it at the same time every day (e.g., in the morning). For patients with renal impairment, an initial dose of 4 mg once daily of candesartan cilexetil is recommended, making this medication unsuitable for initial treatment. For patients with hepatic impairment, an initial dose of 2 mg once daily of candesartan cilexetil is recommended.

Child dose

The safety and efficacy of this medication in adolescents and children under 18 years of age have not been established, and its use is not recommended.

Precautions

This drug can cause serious harm to the fetus, especially in the second and third trimesters of pregnancy, so treatment should be discontinued immediately upon confirmation of pregnancy. This drug should not be administered to patients with specific allergic reactions or with a history of severe liver dysfunction, severe kidney dysfunction, or angioedema. Elderly patients, patients with hyperkalemia, those with impaired liver function, and patients with severe hypotension should be observed carefully when using this drug. Since this medication lowers blood pressure, caution is required in patients with hypotension or heart failure to avoid exacerbating symptoms. It is important to regularly check serum potassium levels and kidney function during treatment with this drug to monitor for abnormalities. This medication may interact with other antihypertensive agents, diuretics, potassium supplements, etc., so consultation with medical personnel is essential. If symptoms such as dizziness, headache, swelling, or skin rash occur during treatment, medical personnel should be informed immediately. Women who are pregnant or breastfeeding should not take this medicine, and if it is absolutely necessary to take it, they should consult with a specialist prior to the decision. This drug is not recommended for use in children or adolescents under 18 years of age as its safety and efficacy have not been established. In case of overdose, severe hypotension, dizziness, tachycardia, etc., may occur, so the dosage should be strictly followed and medical attention should be sought immediately if any adverse symptoms arise. When storing this medication, keep it out of reach of children, and do not transfer it to a different container to maintain quality.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in the mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory distress accompanied by cough and fever, jaundice (yellowing of the skin or eyes), extreme fatigue, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urination

Mild side effects

  • Hemorrhoids
  • gastritis
  • epigastric pain
  • colon polyps
  • pancreatitis
  • chronic gastritis
  • gastroesophageal reflux disease
  • irritable bowel syndrome
  • reflux
  • constipation
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  • nausea
  • abdominal discomfort
  • headache
  • anosmia
  • sensory disturbances
  • elevated serum triglycerides
  • palpitations
  • fatigue
  • myalgia
  • arthralgia
  • bursitis
  • limb pain
  • low back pain
  • pruritus
  • rash
  • eosinophilia
  • hearing impairment
  • dry eyes
  • cystitis
  • acute sinusitis
  • pharyngitis
  • ocular contusion
  • ligament inflammation

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to prevent exposure to air or moisture, ideally at room temperature between 1 and 30 degrees Celsius. Proper storage helps maintain the efficacy of the drug for a longer period.

Appearance and packaging

Appearance

White, double convex, round film-coated tablet

Package unit

30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.