Entiksajeong 5 mg (Memantine Hydrochloride)

Adult dose

This medication is taken orally once daily, at the same time each day. If necessary, it can be taken twice daily. The initial dosage increase is made by increasing 5 mg per week for 3 weeks. First week (Day 1 to 7): 5 mg once daily Second week (Day 8 to 14): 10 mg once daily Third week (Day 15 to 21): 15 mg once daily From the fourth week: 20 mg once daily The recommended maintenance dosage is 20 mg once daily.

This medication should not be used in certain patients. For instance, individuals who have had an allergic reaction to this medication should not take it. Additionally, patients with severely impaired liver function or very poor kidney function should avoid this medication. Caution is needed when using this medication. Patients with epilepsy or those who have had seizures in the past should use this medication carefully. Also, it should not be taken with similar acting drugs such as amantadine, ketamine, or dextromethorphan, as this may worsen side effects. Patients with dietary changes that may increase urine acidity (pH) or certain urinary tract infections should be cautious. Those with uncontrolled heart disease or hypertension should consult a physician before using this medication. Side effects such as dizziness, headache, constipation, drowsiness, and hypertension may occur during treatment. Most are mild or moderately severe, and serious side effects are rare but should be monitored closely. This drug may interact with other medications. Particularly, when taken with levodopa, dopamine agonists, or anticholinergics, the effects or side effects may change. It may also reduce the effectiveness of barbiturates or antipsychotics, and when combined with skeletal muscle relaxants, dosage adjustment may be necessary. Women who are pregnant or may become pregnant should weigh the benefits and risks before taking this medication, and breastfeeding mothers are recommended to discontinue nursing. Children and adolescents under 18 years should not use this medication, as its safety and effectiveness have not been established. In the case of overdose, symptoms may include drowsiness, confusion, dizziness, diarrhea, and in severe cases, psychiatric symptoms or seizures may occur. In such situations, immediate medical attention is required. Finally, this medication may affect the patient's reaction speed, so caution is advised when operating a vehicle or machinery. This medication should be stored out of reach of children, and transferring it to another container is not recommended for quality maintenance.

Serious side effects

• Seizures
• psychotic reactions
• hallucinations
• hypertension
• heart failure
• venous thrombosis/thromboembolism
• respiratory distress

Mild side effects

• Dizziness
• headache
• constipation
• drowsiness
• hypertension
• confusion
• hallucinations
• psychotic reactions
• balance disorders
• gait abnormalities

This medication must be stored in a tightly closed container to protect it from air and moisture. It should also be stored at room temperature, ideally between 1 to 30 degrees Celsius, avoiding excessive heat or cold.

Appearance

White oval film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle