MANTINI 5mg Tablet (Memantine Hydrochloride)

Adult dose

This medication is administered orally once daily, and should be taken at the same time each day. If necessary, it can be dosed as twice a day. The maximum daily dose is 20mg, and to minimize the risk of adverse reactions, the dosage should be increased by 5mg per week over the first 3 weeks. First week (days 1-7): 5mg once daily Second week (days 8-14): 10mg once daily Third week (days 15-21): 15mg once daily

This medication should not be administered to patients who are allergic to its components. It should also not be used in patients with severely impaired liver function or significant renal impairment. Caution is advised in patients with epilepsy, those with a history of seizures, or those with a predisposition to seizures. Additionally, concurrent use with NMDA receptor antagonists such as amantadine, ketamine, or dextromethorphan may increase central nervous system side effects, so they should not be used together. In situations or conditions where the acidity of urine may change, careful monitoring of urine status is necessary. Patients who have recently experienced myocardial infarction, heart failure, or uncontrolled hypertension require caution due to insufficient information about the safety of this drug. While taking this medication, symptoms such as dizziness, headache, constipation, drowsiness, and hypertension may occur, and these symptoms are generally mild to moderate. Psychiatric adverse reactions such as confusion, hallucinations, and psychotic symptoms may occur rarely, so caution is needed. This medication may interact with other drugs; therefore, especially when taken with levodopa, dopamine agonists, anticholinergics, barbiturates, antipsychotics, and skeletal muscle relaxants, consultation with a specialist is advised. Women who are pregnant or of childbearing potential should consult a doctor before taking this medication, and breastfeeding is recommended to be discontinued while on this medication. It is advisable not to use this medication in children or adolescents under 18 years of age, as safety and efficacy have not been established. In case of overdose, central nervous system symptoms or gastrointestinal symptoms may appear, and appropriate medical treatment should be sought immediately. This medication may affect the patient's reaction speed, so caution is necessary when driving or operating machinery. Finally, keep this medication out of the reach of children and do not transfer it to other containers.

Serious side effects

• Seizures
• hallucinations
• psychotic reactions
• heart failure
• venous thrombosis/thromboembolism
• dyspnea
• pancreatitis
• hepatitis

Mild side effects

• Dizziness
• headache
• constipation
• drowsiness
• hypertension
• fungal infections
• drug hypersensitivity reactions
• confusion
• hallucinations
• psychotic reactions

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is important to maintain a storage temperature between 1 to 30 degrees Celsius.

Appearance

White oval film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle