Zadiglimmet Tablets 5/1000 mg (Empagliflozin 2L-Proline, Metformin)

Adult dose

The recommended dosage of this medication is 1 tablet once, twice a day. The dosage should not exceed the maximum recommended daily dosages of empagliflozin 25 mg and metformin 2000 mg for each component and should be determined based on the current treatment regimen, efficacy, and tolerability of each patient. - For patients who cannot adequately control blood sugar with monotherapy of metformin or combined therapies with insulin or other drugs, the recommended dosage is 5 mg empagliflozin twice a day.

This medication is used for the treatment of diabetes and aids in regulating blood sugar levels. This medication should not be used in patients with impaired kidney function or those with acute infections, dehydration, or severe heart conditions. It is also recommended that pregnant or breastfeeding women avoid this medication for safety. Caution is warranted when taking this medication as hypoglycemic symptoms might occur, particularly when used with insulin or other hypoglycemic agents. A rare side effect, severe lactic acidosis, may occur, which can be life-threatening; immediate consultation with a doctor is required if symptoms present. This medication may increase the risk of urinary or genital infections, so immediate treatment should be sought if infectious symptoms occur. Regular monitoring of kidney function and blood sugar status is recommended during treatment, and checking of vitamin B12 levels is also advisable. Before surgery or diagnostic tests involving contrast agents, this medication may need to be discontinued for a specific period, and its resumption should be based on confirmation of normal kidney function. During treatment, caution should be exercised against dehydration or fluid loss, and medical personnel should be informed immediately of any dehydration symptoms. Alcohol consumption should be avoided as it may increase the risk of side effects associated with this medication. Elderly patients or those with impaired kidney function should take this medication with special care, and dosage adjustments may be required. In case of overdose, appropriate medical treatment should be sought immediately, and blood dialysis may be necessary. This medication is not recommended for children as its safety and efficacy have not been established. If any unusual symptoms or discomfort occur during treatment, immediately consult a doctor or pharmacist.

Serious side effects

• Hives
• angioedema
• perineal necrosis
• ketoacidosis
• lactic acidosis
• severe swelling (edema)
• liver dysfunction (jaundice)
• cerebral infarction
• myocardial infarction
• pneumonia

Mild side effects

• Nausea
• vomiting
• diarrhea
• abdominal pain
• loss of appetite
• constipation
• hypoglycemia
• urinary infections
• genital infections
• increased urination

This medication should be stored in a tightly sealed container to avoid exposure to air or moisture. It is advisable to maintain a storage temperature between 1 to 30 degrees Celsius.

Appearance

Biconvex oval film-coated tablet with a yellow color with a brownish tint

Package unit

30 tablets/bottle