Hyundai Minoxidil Tablet 2.5 mg

Adult dose

Adults (12 years and older): The initial dosage is 5 mg of minoxidil administered orally once daily, with a maintenance dose of 10-40 mg divided into 1-2 doses daily. A maximum of 100 mg can be administered daily. The frequency of administration should be adjusted based on the reduction in blood pressure, with once daily administration if the decrease in diastolic pressure is less than 30 mmHg, and divided into 2 doses daily if the decrease is 30 mmHg or more.

Child dose

Pediatric (under 12 years): The initial dosage is 0.2 mg per kg of body weight once daily, with a potential increase of 50-100% until blood pressure is optimally adjusted. For maintenance, 0.25-1 mg per kg of body weight is administered daily.

This drug should not be administered to patients with certain diseases. For example, patients with pheochromocytoma should not use this drug as it may increase catecholamine secretion from the tumor due to its blood pressure-lowering effect. Additionally, patients with pulmonary hypertension due to mitral stenosis, acute myocardial infarction patients, and patients with hypersensitivity to this drug should also not take it. Patients with chronic congestive heart failure, severe renal failure, and angina should be administered this drug with caution and under strict observation by a physician. This drug can cause abnormal hair growth, which primarily appears in specific areas of the face and body, and will return to baseline over time after discontinuation. This side effect can be particularly problematic for children or women, so sufficient explanation should be provided in advance. Furthermore, skin rash or severe allergic reactions may occur, and there may be a decrease in blood cell counts or abnormal liver function, necessitating regular blood tests. Some abnormal findings may appear on an electrocardiogram, but most of these disappear with continued treatment and do not significantly affect heart function. Symptoms of pericardial effusion may rarely occur, especially in patients with poor renal function. In this case, an ultrasound examination should confirm the condition, and treatment methods should be adjusted if necessary. When taking this drug, diuretics are often used together to prevent fluid retention, and weight and electrolyte status should be checked regularly. Due to vasodilatory effects, heart rate may increase, and beta-blockers may be used simultaneously to control this. Patients with impaired renal function or dialysis patients may require dosage adjustments, and myocardial infarction patients may only use this drug after their condition has stabilized. At the beginning of treatment, regular check-ups are required for urinalysis, renal function tests, electrocardiograms, chest X-rays, and echocardiography. This drug can interact with other medications, so caution is needed when taken with guanethidine, some antidepressants, antipsychotic medications, corticosteroids, nonsteroidal anti-inflammatory drugs, etc. Safety during pregnancy has not been established, and it is recommended to avoid use during breastfeeding or to discontinue breastfeeding. There is limited experience in using this drug in children, especially newborns, and it should be administered with caution. In the event of an overdose of this drug, intravenous saline may be administered to help maintain blood pressure and facilitate urine excretion, and sympathomimetics should be avoided as they may cause excessive cardiac stimulation. Specific medications may be used if necessary to restore blood pressure.

Serious side effects

Urticaria, exudative rash, vesicular lesions, Stevens-Johnson syndrome, thrombocytopenia, leukopenia (WBC <3000/mm2), pericardial effusion and cardiac tamponade, severe edema, symptoms suggesting decreased heart function

Mild side effects

Hypertrichosis, increased hair growth and pigmentation, decreased hematocrit, hemoglobin, and red blood cell count, increased ALP, electrocardiogram T-wave changes, pericardial effusion, weight gain, peripheral edema, increased heart rate, temporary elevation of creatinine and BUN, gastrointestinal disturbances, rash, mastalgia, gynecomastia, hemolytic anemia, pulmonary infiltrates, antinuclear antibodies (ANA), headache, intermittent claudication, frequent menstruation, nausea, vomiting

This drug should be stored in a tightly sealed container to avoid exposure to air or moisture. It is best to maintain a storage temperature between 1 degree and 30 degrees Celsius.

Appearance

White round tablet

Package unit

30 tablets/bottle, 300 tablets/bottle