Valdipin Plus Tablet 5/160/12.5 mg (Amlodipine, Valsartan, Chlorthalidone)

Adult dose

This medication is taken once daily as one tablet with water, regardless of meals. It is recommended to take it at the same time each day (e.g., in the morning). For patients whose blood pressure is not controlled with amlodipine/valsartan combination therapy, a dose of 5/80/12.5 mg is administered, and the dosage may be adjusted with intervals of more than 2 weeks based on the patient's blood pressure response. The maximum prescribed dosage for this medication is 10/160/25 mg.

This medication can cause serious harm to the fetus and newborn, especially during pregnancy; therefore, it should be discontinued immediately if pregnancy is confirmed. Patients with impaired liver function or those with ongoing liver disease should exercise caution as severe side effects such as hepatic coma can occur when taking this medication. Patients with severely poor kidney function may experience elevated blood nitrogen levels due to some components of this medication, and kidney function should be closely monitored. Patients allergic to any of the ingredients of this medication or to similar drugs should not use it. Patients with very low blood pressure, severe liver impairment or biliary obstruction, and severe renal impairment should not take this medication. Patients with diabetes or moderate to severe renal impairment should avoid using this medication in combination with certain other drugs. Patients at risk of hyperkalemia or who are prone to increased blood potassium levels should frequently check their potassium levels while taking this medication, and special caution is advised if taking potassium supplements. Patients with fluid or sodium deficiency should replenish their condition before starting this medication, and if symptoms of hypotension occur, immediate lying down and intravenous therapy should be sought as necessary. Patients with heart failure, following myocardial infarction, renal failure, and the elderly should monitor their health more closely while using this medication, and dosage adjustments may be necessary. This medication can cause various side effects including dizziness, headaches, low blood pressure, electrolyte imbalances in the blood, etc.; if any unusual symptoms appear, consult a physician immediately. Special care should be taken as dizziness or drowsiness may occur while driving or operating machinery during the course of this medication. This medication may interact with other drugs; therefore, inform healthcare providers of any other medications being taken. Pregnant or breastfeeding women should not take this medication and should consult healthcare providers if planning to become pregnant or are currently pregnant. Safety and efficacy have not been established for children and adolescents under 18 years of age, so its use is not recommended. In cases of overdose, severe hypotension, shock, and electrolyte abnormalities may occur, necessitating immediate emergency treatment. This medication should be stored in a cool, dry place away from moisture and direct sunlight, and should be kept out of the reach of children. It is advisable not to transfer it to other containers.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, pain in mucous membranes of the mouth/eyes, difficulty breathing or shortness of breath, asthma attacks, respiratory issues along with cough + fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, vision abnormalities, paralysis, urination issues

Mild side effects

Dizziness, headache, increased blood uric acid, increased alanine aminotransferase (ALT), increased aspartate aminotransferase (AST), increased creatine phosphokinase (CPK), elevated blood sugar, increased blood triglycerides (TG), COVID-19, nasopharyngitis, upper respiratory tract infection, eyelid twitching, orthostatic hypotension, chest discomfort, flushing, fatigue, edema, palpitations, vertigo, drowsiness, abdominal pain, nausea, weakness, lethargy

This medication is sensitive to air and moisture, so it must be stored in an airtight container. It is advisable to maintain room temperature between 1 and 30 degrees Celsius for optimal storage, which helps preserve the medication's effectiveness.

Appearance

Pale pink rectangular film-coated tablet

Package unit

30 tablets/bottle