Rinatine Mpa Tablet 25/5 mg (Empagliflozin, Linagliptin)

Adult dose

The recommended starting dose of this medicine is once daily with 10 mg of empagliflozin and 5 mg of linagliptin. If tolerated and further blood sugar control is needed, it may be increased to 25/5 mg once daily. This medicine can be administered regardless of meals, and the tablet should be swallowed whole. Never take double the dose in one day.

This medicine consists of two ingredients, empagliflozin and linagliptin, and is primarily used for the treatment of type 2 diabetes. First, it should not be used by individuals who are allergic to empagliflozin, linagliptin, or any other ingredients in this medicine. It is also not to be administered to patients with type 1 diabetes, diabetic ketoacidosis, or those undergoing dialysis. Second, patients with impaired kidney function should regularly undergo kidney function tests prior to using this medicine, and exercise caution if taking other medications that may affect kidney function. Caution is also necessary for patients with heart failure, and if symptoms of acute pancreatitis occur, the medication should be stopped immediately. Additionally, if symptoms resembling blistering disorders like bullous pemphigoid appear on the skin, consult a doctor immediately. Third, when taking this medicine, side effects such as urinary tract infections, genital infections, hypoglycemia, dehydration, and low blood pressure may occur, so be vigilant for symptoms. Particularly, if taking sulfonylureas or insulin together, the risk of hypoglycemia may increase, so blood sugar levels should be closely monitored. Fourth, dizziness or low blood pressure due to fluid volume loss may occur, so elderly individuals or those with low blood pressure should take extra caution, and if dehydration symptoms occur, the use of this medicine may be temporarily halted. Fifth, this medicine is not recommended for women who are pregnant or breastfeeding, and consultation with a doctor is essential if planning for pregnancy or if already pregnant. Sixth, this medicine has not been confirmed for safety and efficacy in children under the age of 18, and its use is not recommended. Finally, taking this medicine may involve risks during driving or operating machinery due to hypoglycemia, so caution is necessary. Before and during the use of this medicine, discuss thoroughly with your physician, and report any unusual symptoms to healthcare personnel immediately.

Serious side effects

Hives, angioedema, ketoacidosis, pancreatitis, blistering disorders like bullous pemphigoid, severe swelling accompanied by increased blood pressure, severe allergic reactions, severe skin reactions, difficulty breathing, asthma attacks, respiratory difficulties, liver abnormalities (jaundice), severe neurological symptoms (thunderclap headache, confusion, vision changes, paralysis), severe swelling or urinary abnormalities, perineal necrosis (Fournier's gangrene), urosepsis, pyelonephritis, acute kidney injury.

Mild side effects

• Urinary tract infection
• vulvovaginitis
• balanitis
• and other genital infections
• cough
• constipation
• rash
• itching
• increased urination
• hypoglycemia

This medicine should be stored in a tightly closed container to protect it from air and moisture. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius. Proper storage will help preserve the drug's effectiveness and safety for a long time.

Appearance

Pink round film-coated tablet

Package unit

30 tablets/bottle