Medication info
Rodientset Tablet 80/2.5/12.5 mg (Telmisartan, Esamlodipine Nicotinate, Chlorthalidone)

Rodientset Tablet 80/2.5/12.5 mg (Telmisartan, Esamlodipine Nicotinate, Chlorthalidone)

Prescription medication경구
Ingredient · strength
Telmisartan›80mg / 1 tabletS-Amlodipine Nicotinate›3.253mg / 1 tabletChlorthalidone›12.5mg / 1 tablet
Manufacturer / importer
한림제약(주)
Appearance
An oval three-layer tablet with the lower layer being light blue and the upper and middle layers being white to light yellow.
Packaging
30 tablets/bottle
Approval status
Active

MFDS item code 202502784 · Approved 2025.10.28 · Insurance code 645307310

Summary

Main use
Improvement in blood pressure control for essential hypertension.
Who takes it
Adults
Adult dose
The recommended dosage for adults is to take one tablet once a day with water, regardless of meals. It is advisable to take it at the same time every day (e.g., in the morning). For patients whose blood pressure is not controlled with the combination of telmisartan and esamlodipine (amlodipine), this medication of 40/2.5/12.5 milligrams may be administered, and the dosage should be adjusted with an interval of more than two weeks based on the patient's blood pressure response.

Ingredients

Manufacturer
한림제약(주)

Efficacy & effects

Improvement in blood pressure control for essential hypertension.

  • Essential hypertension
View approved original text

This medication is used for essential hypertension, specifically for patients whose blood pressure is not adequately controlled, through a combination therapy of telmisartan and esamlodipine. This treatment effectively lowers blood pressure by having the two drugs work together and helps reduce the risk of cardiovascular disease occurrences. Hence, it is effective for improving blood pressure management and supports stable blood pressure control.

How to take

Adult dose

The recommended dosage for adults is to take one tablet once a day with water, regardless of meals. It is advisable to take it at the same time every day (e.g., in the morning). For patients whose blood pressure is not controlled with the combination of telmisartan and esamlodipine (amlodipine), this medication of 40/2.5/12.5 milligrams may be administered, and the dosage should be adjusted with an interval of more than two weeks based on the patient's blood pressure response.

Precautions

This medication may pose a severe risk to the fetus, particularly during the second and third trimesters, therefore it should not be taken by pregnant women or women who could become pregnant. Patients with impaired liver function or those with progressing liver disease may face serious issues such as hepatic coma while taking this medication, thus caution is advised. Patients with severe renal disease should use this medication carefully as it may worsen kidney function. Individuals with hypersensitivity to any of the components in this medication, those with certain heart diseases, biliary obstruction disease, women in mid to late pregnancy, and nursing mothers should not use this medication. Special caution is required for patients with diabetes or renal impairment, hypotension, electrolyte imbalance, or a history of gout in addition to hypertension or heart problems. This medication can cause various side effects including dizziness, hypotension, edema, headache, gastrointestinal disorders; if symptoms are severe, consultation with a doctor is advised. Blood pressure may drop significantly, so it is necessary to start the dosage gradually under medical supervision when initially taking it or changing the dosage, while closely monitoring your condition. This medication may interact with other antihypertensive drugs, diuretics, cardiac medications, etc., so individuals should inform their healthcare provider about any other medications they are taking. Nursing mothers should not take this medication, and it is recommended to discontinue use during pregnancy and switch to an alternative medication. Elderly patients may experience stronger effects from this medication, so starting with a lower dose and gradually increasing it is safer. In case of overdose, symptoms such as hypotension, dizziness, and abnormal heart functions may appear, and immediate medical attention is essential for proper treatment. This medication should be kept in a cool, dry place, away from direct sunlight, and out of reach of children.

Side effects and when to seek care immediately

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, mucosal pain in mouth/eyes, wheezing or difficulty breathing, asthma attacks, cough + fever accompanied respiratory difficulties, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

  • Dizziness
  • headache
  • back pain
  • rash
  • abdominal pain
  • nausea
  • constipation
  • lethargy
  • hypokalemia
  • hyponatremia
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  • gingivitis
  • insomnia
  • visual disturbances
  • chest discomfort
  • chest pain
  • vascular edema
  • musculoskeletal stiffness
  • positional dizziness
  • itching
  • increased sweating
  • erythema
  • myalgia
  • fatigue
  • cough
  • nausea
  • pain
  • facial edema
  • thrombocytopenia
  • anemia
  • diarrhea
  • abdominal pain
  • urinary tract infection
  • erectile dysfunction
  • muscle cramps
  • bradycardia
  • thrombocytopenia

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air or moisture and should be stored in a tightly sealed container. It is advisable to keep the medication at room temperature between 1 and 30 degrees Celsius, ensuring effectiveness and safety.

Appearance and packaging

Appearance

An oval three-layer tablet with the lower layer being light blue and the upper and middle layers being white to light yellow.

Package unit

30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.