Empagliflozin and Linagliptin Tablet 10/5 mg (Empagliflozin, Linagliptin (Unmodified))

Adult dose

The recommended starting dose of this medication is 10 mg of empagliflozin and 5 mg of linagliptin once daily. If well tolerated and additional blood sugar control is needed, the dose can be increased to 25/5 mg once daily. This medication can be taken regardless of meals. The tablet should be swallowed whole. If a dose is missed, take it as soon as remembered, but skip it if the next dosing time is within 12 hours.

This medication consists of two active ingredients, empagliflozin and linagliptin, and is used in the treatment of diabetes. Firstly, this medication should not be administered to certain patients. For example, individuals with allergic reactions to any components of this medication or other constituents, patients with type 1 diabetes or diabetic ketoacidosis, and those undergoing dialysis should not take this medication. Patients with impaired kidney function, heart failure, or a history of pancreatitis need to exercise special caution when taking this medication. If pancreatitis is suspected, the medication should be stopped immediately, and symptoms of pancreatitis include persistent severe abdominal pain. Additionally, a skin condition known as bullous pemphigoid may occur during the use of this medication, so if any blisters or erosion appear on the skin, immediate consultation with a physician is necessary. The most common side effect of this medication is urinary tract infections, which may occur more frequently in women. Genital fungal infections may also occur, so caution is advised. Symptoms of hypoglycemia are rare with this medication alone, but the risk of hypoglycemia may increase when taken in conjunction with other diabetes medications such as insulin or sulfonylureas, so blood sugar management should be closely monitored. This medication may lower blood pressure, so patients with hypotension or cardiovascular diseases need to be careful, and it is advised to consult a physician in situations where dehydration or fluid loss is a concern. It is recommended that women who are pregnant or breastfeeding avoid taking this medication, and its safety and efficacy have not been established in children under 18 years of age, hence it should not be used in this population. During the use of this medication, caution is advised while driving or operating machinery, especially if there is a risk of hypoglycemia. Finally, this medication may interact with other drugs, so if taking medications such as insulin, sulfonylureas, diuretics, or lithium, it is essential to consult a physician or pharmacist. If any abnormal symptoms occur while taking this medication, it is important to consult healthcare professionals immediately.

Serious side effects

Hives, angioedema, ketoacidosis, pancreatitis, bullous pemphigoid, severe edema accompanied by elevated blood pressure, chest tightness, difficulty breathing, cold sweats, pallor, severe allergic reactions, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, severe skin adverse reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice).

Mild side effects

• Urinary tract infections
• vulvovaginal candidiasis
• vulvitis
• balanitis
• and other genital infections
• hypoglycemia
• thirst
• cough
• constipation
• oral ulcer formation

This medication should be stored in a tightly sealed container to avoid exposure to air or moisture. It is important to maintain a storage temperature between 1 and 30 degrees Celsius.

Appearance

Yellow film-coated tablet with a round, biconvex shape

Package unit

Box - 30 tablets/box [10 tablets/PTP x 3], Bottle - 30 tablets/bottle, Bottle - 100 tablets/bottle