Multinew 5

Adult administration

Use as prescribed by a physician, adjusting dosage based on plasma trace element levels. - For patients receiving metabolically stable parenteral nutrition: Zinc 2.5–4mg daily, Copper 0.5–1.5mg daily, Manganese 0.15–0.8mg daily, Chromium 10–15µg daily, Selenium 20–40µg daily. - For patients with acute inflammatory states: 4.5–6mg daily. - For patients with metabolically stable small bowel fluid losses: additional.

Child administration

Children under 5 years: Zinc 100µg per kg of body weight daily, Copper 20µg per kg of body weight daily, Manganese 2–10µg per kg of body weight daily, Chromium 0.14–0.20µg per kg of body weight daily, Selenium 1 day per body weight.

This medication contains benzyl alcohol, which can cause severe respiratory problems in premature or newborn infants; therefore, it should not be used. Injecting directly into a vein without dilution can cause phlebitis, so it must be diluted before use. This medication is a hypotonic solution and should only be used in mixed injections; it should be avoided for standalone administration. If any toxic symptoms occur due to any component, administration should be stopped immediately, and particular caution should be exercised regarding aluminum accumulation in patients with poor renal function or premature infants. It is important to regularly check the concentration of trace elements in the blood to adjust the appropriate dosage, and patients with impaired kidney or biliary function should be aware of the risk of accumulation of specific trace elements. For diabetic patients, the medication may impact blood sugar control, so diabetes treatment should always be verified. Due to insufficient evidence of safety in pregnant women, it should be administered cautiously only when the benefits of treatment outweigh the risks. In case of overdose, trace elements like zinc, copper, and selenium can cause toxicity, so immediate consultation with healthcare professionals is required if symptoms occur. Calcium supplementation may help in preventing toxicity. This medication must be used according to a doctor's prescription, prepared in a sterile environment, and checked for discoloration or foreign substances in the solution before administration.

Serious side effects

• Hypotension
• pulmonary edema
• jaundice
• decreased urine output
• peripheral edema
• coma.

Mild side effects

• Hyperhidrosis
• decreased consciousness
• blurred vision
• tachycardia
• hypothermia
• diarrhea
• vomiting
• hair loss
• nail weakness
• dermatitis

This medication should be stored in a sealed container to prevent air or moisture ingress. Additionally, it is advisable to store it at room temperature between 15 and 30 degrees to maintain the drug's efficacy.

Appearance

A clear, colorless or pale blue transparent solution contained in a colorless transparent vial for injection.

Package unit

10 vials/box [10mL/vial]