Pitaef Tablets (Pitavastatin Calcium, Fenofibrate)

Adult dose

As a recommended dose, take 1 tablet once daily immediately after a meal.

This medication is used to lower blood lipid levels. When taking this medication, caution is needed as muscle-related symptoms such as muscle pain, muscle weakness, and cramping may occur. Particularly, elderly individuals, women, those with poor renal function, individuals with uncontrolled hypothyroidism, and those with a history of muscle disorders should be more cautious. If any abnormal muscle symptoms develop, immediately consult a doctor and perform blood tests to check for muscle damage. This medication may affect liver function, so individuals with liver diseases or elevated liver enzyme levels should have regular liver function tests, and if symptoms of hepatitis appear, the medication should be discontinued immediately. This medication should not be used in patients with moderate to severe renal impairment, and caution is required in mild renal impairment patients. Regular monitoring of serum creatinine levels should be conducted to monitor changes in kidney function. This medication should not be administered to patients with pancreatitis or gallbladder diseases, and if gallstones are suspected, tests should be performed to confirm before considering use. Additionally, this medication may increase the risk of muscle toxicity when taken with other lipid-lowering agents, especially fibrates, statins, and niacin, therefore it should be used with extreme caution when combined. Pregnant women or those who may become pregnant, as well as nursing mothers, should not take this medication, and it is not to be administered to children or adolescents under 18 years of age. Symptoms such as dizziness or headache may occur during treatment, so care should be taken when driving or operating machinery. Prior to taking this medication, a sufficient diet and exercise regimen should be practiced, and if the treatment is ineffective, the medication should be discontinued. In case of overdose, there is no specific antidote available, so symptomatic treatment should be provided, and it should be kept out of reach of children.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, angioedema, pancreatitis, jaundice, liver abnormalities (jaundice), sudden and very severe headache, paralysis, rhabdomyolysis, pulmonary embolism, deep vein thrombosis, thromboembolism, interstitial lung disease, DRESS syndrome, severe skin reactions (erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis), rhabdomyolysis with or without acute renal failure, severe cases

Mild side effects

• Pharyngitis
• upper respiratory infection
• increased ALT
• increased AST
• increased GGT
• abnormal liver function tests
• gastroesophageal reflux disease
• nausea
• headache
• dizziness

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. It is recommended to maintain a storage temperature between 1 degree and 30 degrees Celsius to preserve the drug's effectiveness for a longer period.

Appearance

White, oblong, film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle