Siloduo Sustained Release Tablet 200/20 mg (Cilostazol, Rosuvastatin)

Adult dose

Take 1 tablet once daily orally on an empty stomach, avoiding meals. Do not crush or chew this medication; swallow the whole tablet.

This medication is used to improve blood circulation and control cholesterol levels. Firstly, when taking this medication, it may cause an increased heart rate which can lead to symptoms of chest pain like angina, so it is essential to observe for these symptoms closely. Those with allergies to this medication or its components should not use it, and patients with a tendency to bleed, those at a high risk of bleeding, heart failure, severely impaired liver or kidney function, and individuals with muscle disorders should also avoid this medication. Furthermore, pregnant or breastfeeding women, as well as women of childbearing age not using adequate contraception, should not take this medication. Caution is necessary if taking other drugs that affect blood clotting or anticoagulants, antiplatelet agents, and thrombolytics, as this may increase the risk of bleeding. This medication may increase blood concentration and consequently side effects when taken with food, so it is recommended to take it on an empty stomach, ideally with a 3-hour interval between meals and medication. During treatment, symptoms such as myalgia, lethargy, headache, dizziness, indigestion, diarrhea, constipation, and edema may occur; should these symptoms persist or worsen, it is essential to consult a physician. In particular, if sudden muscle pain or weakness occurs, or if there is a feeling of powerlessness, immediate medical attention is advised. As liver function abnormalities may arise, regular liver function tests should be performed, and if jaundice, severe fatigue, or darkening of urine occurs, the physician must be notified without delay. As this medication is metabolized by specific enzymes, possible interactions with other medications exist; therefore, it is mandatory to disclose any concurrent medications. During pregnancy, it might harm the fetus, so it should be avoided, and in breastfeeding cases, it is safer to discontinue breastfeeding. Elderly patients may have reduced physiological function, requiring extra caution during administration. In the case of overdose, severe headache, diarrhea, hypotension, and cardiac rhythm disturbances may occur, necessitating immediate medical intervention, and this drug is difficult to eliminate through dialysis. Lastly, dizziness might occur while driving or operating machinery during the course of this medication, so take care.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, severe rash with fever, blisters, skin peeling, oral/eye mucosal pain, shortness of breath or difficulty in breathing, asthma attacks, visual disturbances, sudden severe headache, thunderclap headache, seizures, confusion, paralysis, skin or eyes turning yellow (jaundice), overall extreme lethargy, significantly reduced urine output, generalized severe swelling and hypertension

Mild side effects

Headache, dizziness, diarrhea, abdominal pain, constipation, indigestion, dry mouth, upper abdominal pain, peripheral edema, fatigue, fever, dryness, cough, non-cardiogenic dyspnea, obstructive sleep apnea syndrome, increased blood creatine phosphokinase levels, increased blood creatinine, elevated aspartate aminotransferase, palpitations, coronary artery disease, tachycardia, pruritus, rash, bruising, bone fractures, ligament sprains, thermal burns

This medication should be stored in a tightly sealed container to prevent air exposure, and it is advisable to store it at a temperature between 1 and 30 degrees Celsius. When stored this way, the drug's efficacy is well-maintained and degradation is prevented.

Appearance

White rectangular sustained-release film-coated tablet

Package unit

Bottle - 30 tablets/bottle, Bottle - 100 tablets/bottle