Empagliflozin 25/5 mg (Empagliflozin, Linagliptin)

Adult dose

The recommended starting dose is 10 mg of empagliflozin and 5 mg of linagliptin once daily. If additional blood sugar control is needed and the patient tolerates the initial dose, the dose may be increased to 25/5 mg once daily. Continue with the existing dosing regimen. This medication can be taken regardless of meals, and the tablet should be swallowed whole. If a dose is missed, it should be taken as soon as remembered, but if the next scheduled dose is within 12 hours, skip the missed dose and continue with the normal schedule.

This medication contains two ingredients, empagliflozin and linagliptin, and is primarily used for the treatment of diabetes. First, this medication should not be used by patients with allergies to empagliflozin or linagliptin, or to other ingredients contained in the medication, nor should it be used by patients with type 1 diabetes, diabetic ketoacidosis, or those on dialysis. Caution should be exercised when using in patients with impaired kidney function, heart failure, a history of pancreatitis, or suspected bullous pemphigoid, a skin condition. The most common side effect associated with this medication during usage is urinary tract infection, while rare but serious side effects including ketoacidosis, pancreatitis, hypersensitivity reactions, and hypoglycemia may also occur. Particularly, there is a risk of hypoglycemia when this medication is taken with insulin or sulfonylureas; caution is warranted. Also, symptoms of low blood pressure or dehydration due to fluid loss may emerge, so those being treated for hypertension, elderly patients, and individuals with a history of low blood pressure should exercise additional caution when taking this medication. This medication may increase the risk of urinary tract infections and genital fungal infections, so if infection symptoms appear, immediate consultation with healthcare providers is recommended. Women who are pregnant or breastfeeding are advised not to use this medication unless specifically instructed; it is recommended to stop breastfeeding during treatment. Use in children under 18 years is not recommended due to the lack of established safety and efficacy.

Serious side effects

• Hives
• angioedema
• ketoacidosis
• pancreatitis
• bullous pemphigoid
• pneumonia
• acute kidney injury
• acute pyelonephritis
• sepsis
• heart failure

Mild side effects

• Urinary tract infection
• vaginitis
• vulvitis
• balanitis
• nasopharyngitis
• cough
• constipation
• mouth ulcers
• itching
• rash

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. The proper storage temperature is room temperature between 1°C and 30°C. Avoid storage in excessively hot or cold places.

Appearance

Pink, round, biconvex film-coated tablet

Package unit

Bottle - 30 tablets/bottle, Bottle - 100 tablets/bottle