Alphael Soft Capsule 0.5 Micrograms (Alfacalcidol)

Adult dose

Chronic kidney failure, osteoporosis: Administer orally once daily at 0.5 to 1 microgram as alfacalcidol. Hypoparathyroidism, other diseases due to vitamin D metabolic disorders: Administer orally once daily at 1 to 4 micrograms.

Child dose

Osteoporosis: Administer orally once daily at 0.01 to 0.03 micrograms per kg of body weight. Other diseases: Administer orally once daily at 0.05 to 0.1 micrograms per kg of body weight.

This drug should not be taken by patients with hypercalcemia, hyperphosphatemia, or hypermagnesemia, or by those whose calcium and phosphorus product in the blood exceeds a certain level, and by individuals with alkalosis. Furthermore, those with vitamin D toxicity symptoms or allergies to this drug and its ingredients should also avoid taking it. While taking this drug, it should not be combined with magnesium-containing medications, vitamin D preparations, calcium-containing agents, or certain diuretics, as these can dangerously increase blood calcium levels. For those who are breastfeeding, safety has not been sufficiently established, so it is better to avoid use if possible, and if unavoidable, stopping breastfeeding is recommended. Pregnant women or women who may become pregnant should consult a doctor before taking this medication due to the risk of harm to the fetus, and caution should be taken by children, the elderly, and patients on specific medications, with advice from specialists. Regular blood tests to check calcium levels and kidney function should be performed during treatment, and if any abnormal symptoms occur, use should be stopped immediately, and medical advice should be sought. Symptoms of hypercalcemia may include indigestion, nausea, vomiting, muscle cramps, headache, insomnia, heart palpitations, and reduced kidney function, so caution is necessary if these symptoms appear. This drug helps regulate calcium and phosphorus levels, so it is important to adhere strictly to dietary guidelines and dosage instructions, and emergency treatment may be required in case of overdose. Lastly, store this medication in a cool, dry place out of reach of children, avoiding direct sunlight, and do not transfer to other containers to maintain the quality of the medication.

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, breathing abnormalities with cough and fever, jaundice of the skin or eyes, systemic fatigue, severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, markedly reduced urine output, severe systemic swelling, blood pressure changes.

Mild side effects

• Loss of appetite
• nausea
• vomiting
• diarrhea
• constipation
• stomach pain
• discomfort in the stomach area
• abdominal bloating
• indigestion
• thirst

This medication should be stored in a tightly sealed container to prevent air and moisture from entering, and it is recommended to keep it at room temperature between 1 to 30 degrees Celsius. Storing it in this manner will help maintain the drug's efficacy and safety.

Appearance

A transparent oval soft capsule of amber color containing a colorless to light yellow transparent emulsion.

Package unit

240 capsules/box [10 capsules/PTP×24], 60 capsules/box [10 capsules/PTP×6]