Empagliflozin and Metformin Hydrochloride Extended-Release Tablet 5/750 mg (Empagliflozin, Metformin Hydrochloride)

Adult dose

This medication is taken orally once daily in the evening with meals. For the 10/1000 mg extended-release tablet or the 25/1000 mg extended-release tablet, take 1 tablet once daily. For patients taking the 5/1000 mg extended-release tablet, 12.5/1000 mg extended-release tablet, 5/750 mg extended-release tablet, or 12.5/750 mg extended-release tablet, take 2 tablets simultaneously once daily. Increase the dosage of metformin hydrochloride as necessary.

This medication is used for the treatment of diabetes and contains two components that help control blood sugar. It is essential to verify normal kidney function before taking this medication, and it should not be administered to patients with impaired kidney function. This drug should not be used in patients with serious illnesses such as severe renal impairment, acute heart failure, acute myocardial infarction, or severe infections. Additionally, individuals allergic to any components of this medication should not take it. This medication can cause a rare but very serious side effect known as lactic acidosis, so special caution is required in cases of dehydration, hypoxia, or liver dysfunction. When used in combination with other diabetes medications, hypoglycemia may occur, so dosage adjustments may be necessary when used together with insulin or sulfonylureas. This drug may increase the risk of genital and urinary tract infections, so consult a doctor immediately if any infection symptoms occur. Regular blood tests are important to monitor kidney function and vitamin B12 levels during treatment. It is advisable for pregnant women, women of childbearing potential, or nursing mothers to avoid using this medication. Elderly patients or those at risk of fluid loss should be cautious about dehydration and low blood pressure and may need to temporarily discontinue the drug if necessary. Patients scheduled for surgery should stop taking this medication 48 hours prior to surgery and resume only after confirming normal kidney function post-surgery. This drug should be swallowed whole and not chewed or crushed, and its coating may appear in stools, which is normal. Overdose can cause severe side effects like lactic acidosis, so immediate medical attention is required for any unusual symptoms. It is advisable to avoid excessive alcohol consumption while taking this medication, and any changes in symptoms or adverse reactions should be reported to a healthcare professional immediately.

Serious side effects

• Hives
• angioedema
• perineal necrosis
• ketoacidosis
• lactic acidosis
• decreased blood pH
• severe swelling
• myocardial infarction
• cerebral infarction
• seizures

Mild side effects

• Hypoglycemia
• urinary tract infections
• genital infections
• increased urination
• nausea
• vomiting
• diarrhea
• abdominal pain
• loss of appetite
• constipation

This medication should be stored in a tightly sealed container, protected from air and moisture, and maintained at room temperature between 1 to 30 degrees Celsius. Proper storage will safely preserve the medication's effectiveness.

Appearance

Pale pink, oval-shaped extended-release film-coated tablet

Package unit

30 tablets/bottle