Empagliflozin/Metformin Extended-Release Tablet 5/1000 mg (Empagliflozin, Metformin Hydrochloride)

Adult dose

In antidiabetic therapy, the dosage of this medication is determined based on each component's maximum recommended daily dose of Empagliflozin 25 mg and extended-release Metformin Hydrochloride 2000 mg, considering each patient's current therapeutic regimen, efficacy, and tolerability. This medication is taken once daily in the evening with meals to reduce gastrointestinal adverse reactions related to Metformin. This medication is 10/1000 mg extended-release.

This medication helps control blood sugar levels. However, there are several important points to be aware of when using it. First, this medication can rarely cause a serious condition called lactic acidosis. Lactic acidosis can build up excessive lactate in the body, becoming dangerous, so if any unusual symptoms or discomfort occur while taking this drug, consult your doctor immediately. Second, hypoglycemia may occur when used with other diabetes medications, so caution is needed, especially when combined with insulin or sulfonylureas. Third, patients with poor kidney function, acute kidney disease, cardiovascular diseases such as heart failure or acute myocardial infarction, and those with liver dysfunction should not use this medication. Fourth, this medication should be temporarily discontinued before and after tests using iodine contrast agents, and should be resumed only after normal kidney function is confirmed. Fifth, patients about to undergo surgery should stop taking this medication 48 hours before surgery and resume only after confirming normal renal function post-surgery. Sixth, this medication may cause fluid volume loss; therefore, special caution is required when symptoms such as dehydration, diarrhea, or vomiting occur. Seventh, women who are pregnant or may become pregnant should avoid this medication, and it should also be avoided while breastfeeding. Eighth, elderly patients or those with impaired kidney function should consult with a doctor before taking this medication and should undergo regular kidney function tests. Ninth, avoiding alcohol consumption during treatment with this medication is advisable, as alcohol can increase the risk of lactic acidosis. Finally, this medication is in a swallowable tablet form and should not be crushed or chewed, but swallowed whole. Sometimes, the tablet coating may be excreted in the stool, but this is normal. If any unusual symptoms occur while taking this medication or if there are any concerns, it is essential to consult healthcare professionals for appropriate action.

Serious side effects

• Urticaria
• angioedema
• necrotizing fasciitis
• ketoacidosis
• lactic acidosis
• urosepsis
• pyelonephritis
• myocardial infarction
• cerebral infarction
• liver damage

Mild side effects

• Hypoglycemia
• urinary tract infection
• genital infection
• increased urination
• nausea
• vomiting
• diarrhea
• abdominal pain
• loss of appetite
• constipation

This medication should be stored in a tightly closed container to protect it from exposure to air and light. It is important to maintain storage temperatures between 1 to 30 degrees Celsius.

Appearance

Pale yellow oval extended-release film-coated tablet

Package unit

30 tablets per bottle