Medication info
Candeval Tablets 16/2.5mg (Candesartan Cilexetil, Esamlodipine Besilate)

Candeval Tablets 16/2.5mg (Candesartan Cilexetil, Esamlodipine Besilate)

Prescription medicationTablet경구
Ingredient · strength
Candesartan Cilexetil›16mg / 1 tabletS-Amlodipine Besylate 2.5 Hydrate›3.74mg / 1 tablet
Manufacturer / importer
현대약품(주)
Appearance
White, biconvex, round film-coated tablet
Packaging
30 tablets/bottle
Approval status
Active

MFDS item code 202501885 · Approved 2025.07.24 · Insurance code 642005380

Summary

Main use
Improvement in blood pressure control for essential hypertension
Who takes it
Adults · Children
Adult dose
The recommended dose of this medication is 1 tablet once daily, taken with water regardless of meals. It is advised to take it at the same time each day (e.g., in the morning). - 8/2.5mg: For patients whose blood pressure is not adequately controlled with Candesartan Cilexetil 8mg or Esamlodipine 2.5mg (Amlodipine 5mg). - 16/2.5mg: Candesartan Cilexetil 16mg.
Child dose
The safety and efficacy of this medication have not been established in individuals under the age of 18, and its use is not recommended.

Ingredients

Manufacturer
현대약품(주)

Efficacy & effects

Improvement in blood pressure control for essential hypertension

  • Essential hypertension
View approved original text

This medication is used when patients with essential hypertension have difficulty controlling blood pressure with monotherapy. By using Candesartan Cilexetil and Esamlodipine (Amlodipine) together, it effectively lowers and helps control blood pressure. It is used to reduce the risk of cardiovascular complications and improve overall blood pressure management.

How to take

Adult dose

The recommended dose of this medication is 1 tablet once daily, taken with water regardless of meals. It is advised to take it at the same time each day (e.g., in the morning). - 8/2.5mg: For patients whose blood pressure is not adequately controlled with Candesartan Cilexetil 8mg or Esamlodipine 2.5mg (Amlodipine 5mg). - 16/2.5mg: Candesartan Cilexetil 16mg.

Child dose

The safety and efficacy of this medication have not been established in individuals under the age of 18, and its use is not recommended.

Precautions

This medication can cause serious harm to the fetus and newborn, especially during the second and third trimesters of pregnancy, so it should be discontinued immediately if pregnancy is confirmed. This medication should not be used in patients with specific allergic reactions, pregnant or breastfeeding women, or patients with severe liver or kidney impairment. Caution is also advised when used in patients with very low blood pressure, heart valve problems, impaired kidney function, and in children and adolescents under the age of 18. While taking this medication, symptoms such as dizziness, headache, gastrointestinal discomfort, edema, and fatigue may occur, and rare side effects like liver dysfunction or blood disorders may arise. It is particularly important to monitor for serious side effects such as dangerously low blood pressure, hyperkalemia, or kidney function deterioration through regular blood pressure and blood tests. Care should be taken when taking this medication with other antihypertensives, diuretics, potassium supplements, and it is advisable to avoid grapefruit juice, as it may enhance the medication's effect. Women who are pregnant or planning to become pregnant should not take this medication, and breastfeeding women are advised to discontinue breastfeeding while taking this medication. In case of overdose, symptoms such as severe hypotension, dizziness, or rapid heartbeat may occur, and immediate medical attention should be sought for appropriate treatment. This medication should be kept out of reach of children, and it is essential not to transfer it to other containers to maintain the safety and effectiveness of the medication.

Side effects and when to seek care immediately

Serious side effects

  • Rash
  • severe swelling (edema)
  • chest tightness
  • difficulty breathing
  • cold sweat
  • pallor
  • severe rash accompanied by high fever
  • blisters
  • peeling skin
  • oral/eye mucosal pain
Show 12 more
  • breathlessness or difficulty breathing
  • asthma attack
  • cough with fever
  • yellowing of skin or eyes (jaundice)
  • extreme lethargy
  • sudden and severe headaches
  • thunderclap headache
  • seizures
  • confusion
  • vision abnormalities
  • paralysis
  • and urination issues.

Mild side effects

  • Hemorrhoids
  • gastritis
  • upper abdominal pain
  • colon polyps
  • pancreatitis
  • chronic gastritis
  • gastroesophageal reflux disease
  • irritable bowel syndrome
  • reflux
  • constipation
Show 24 more
  • nausea
  • abdominal discomfort
  • dizziness
  • headache
  • head discomfort
  • anosmia
  • sensory abnormalities
  • increased triglyceride levels
  • palpitations
  • chest discomfort
  • fatigue
  • peripheral edema
  • facial swelling
  • chest pain
  • myalgia
  • joint pain
  • mucous cysts
  • limb pain
  • back pain
  • itching
  • rash
  • eosinophilia
  • hearing impairment
  • and eye symptoms.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to protect it from air and moisture. It is best to maintain storage temperature between 1 to 30 degrees Celsius at room temperature.

Appearance and packaging

Appearance

White, biconvex, round film-coated tablet

Package unit

30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

No questions yet.

For anything that needs medical judgment, consult a doctor or pharmacist.

Related searches

Search tags

Suggested searches

This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.