Medication info
Candesartan E/S Tablet 16/2.5 mg (Candesartan, Amlodipine)

Candesartan E/S Tablet 16/2.5 mg (Candesartan, Amlodipine)

Prescription medicationTablet경구
Ingredient · strength
Candesartan Cilexetil›16mg / 1 tabletS-Amlodipine Besylate 2.5 Hydrate›3.74mg / 1 tablet
Manufacturer / importer
명문제약(주)
Appearance
White, biconvex, round film-coated tablet
Packaging
30 tablets/bottle
Approval status
Active

MFDS item code 202501848 · Approved 2025.07.22 · Insurance code 649808360

Summary

Main use
Improvement of blood pressure control in essential hypertension
Who takes it
Adults · Children
Adult dose
The recommended dosage for this medication is one tablet once daily, taken with water regardless of meals. It is recommended to take it at the same time every day (e.g., in the morning). For patients with kidney impairment, an initial dose of 4 mg of Candesartan Cilexetil once daily is recommended, so it is not advisable to administer this medication for initial treatment. For patients with liver impairment, an initial dose of 2 mg of Candesartan Cilexetil once daily is recommended.
Child dose
The safety and efficacy of this medication in adolescents and children under 18 years of age have not been established, and its use is not recommended.

Ingredients

Manufacturer
명문제약(주)

Efficacy & effects

Improvement of blood pressure control in essential hypertension

  • Essential hypertension
View approved original text

For patients with essential hypertension, this medication can be used to effectively manage blood pressure when blood pressure is insufficiently controlled by monotherapy with Candesartan Cilexetil or S-Amlodipine (Amlodipine). This medication helps lower blood pressure and maintain heart and vascular health. Consistent use may reduce the risk of complications caused by hypertension. Therefore, this medication is used for the treatment of essential hypertension where blood pressure control is difficult.

How to take

Adult dose

The recommended dosage for this medication is one tablet once daily, taken with water regardless of meals. It is recommended to take it at the same time every day (e.g., in the morning). For patients with kidney impairment, an initial dose of 4 mg of Candesartan Cilexetil once daily is recommended, so it is not advisable to administer this medication for initial treatment. For patients with liver impairment, an initial dose of 2 mg of Candesartan Cilexetil once daily is recommended.

Child dose

The safety and efficacy of this medication in adolescents and children under 18 years of age have not been established, and its use is not recommended.

Precautions

This medication can cause serious harm to the fetus when taken during pregnancy, especially in the second and third trimesters, so it should be discontinued immediately upon confirmation of pregnancy. This medication should not be used in patients with allergies to specific medications, pregnant or breastfeeding women, patients with severe liver or kidney damage, and patients with certain heart diseases or vascular disorders. Particular caution should be exercised when using this medication in elderly patients or those with high serum potassium levels, impaired liver function, or hypotensive patients. Patients with reduced kidney function or those who have recently undergone kidney transplants also require careful monitoring. While taking this medication, various side effects such as dizziness, headache, dyspepsia, swelling, myalgia, and rash may occur, and if unusual symptoms appear, patients should consult a doctor or pharmacist. Patients with heart failure or kidney disease should regularly monitor their blood pressure and kidney function as well as serum potassium levels, and caution is needed when combining this medication with other antihypertensives or specific diuretics due to an increased risk of side effects. This medication can interact with other drugs, so patients must inform their healthcare provider of any additional medications being taken, and it is advisable to avoid taking it with grapefruit juice. Dizziness or drowsiness may occur while driving or operating machinery, requiring caution, and there is a risk of fainting due to sudden drops in blood pressure, so patients should rest immediately if symptoms occur. The safety and efficacy of this medication in children and adolescents have not been established, so its use is not recommended. In case of overdose, symptoms may include hypotension, dizziness, and tachycardia, and immediate medical treatment should be sought, as this medication is not removed by dialysis and requires specialized treatment. When stored, this medication should be kept in an airtight container that prevents air and moisture exposure, and should be kept at room temperature between 1 degree and 30 degrees Celsius. Proper storage can help maintain the effectiveness of the medication and prevent degradation.

Side effects and when to seek care immediately

Serious side effects

Urticaria, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, peeling skin, painful mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attack, respiratory problems accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, lightning headache, seizures, confusion, visual disturbances, paralysis,

Mild side effects

  • Hemorrhoids
  • gastritis
  • epigastric pain
  • colon polyps
  • pancreatitis
  • chronic gastritis
  • gastroesophageal reflux disease
  • irritable bowel syndrome
  • reflux
  • constipation
Show 24 more
  • nausea
  • abdominal discomfort
  • dizziness
  • headache
  • head discomfort
  • anosmia
  • sensory abnormalities
  • elevated serum triglycerides
  • palpitations
  • chest discomfort
  • fatigue
  • peripheral edema
  • facial swelling
  • chest pain
  • myalgia
  • arthralgia
  • mucous cysts
  • limb pain
  • low back pain
  • itching
  • rash
  • eosinophilia
  • hearing impairment
  • eye

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container that can block air and moisture, and it is advisable to keep it at room temperature between 1 degree and 30 degrees Celsius. Proper storage helps maintain the effectiveness and prevent deterioration of the medication.

Appearance and packaging

Appearance

White, biconvex, round film-coated tablet

Package unit

30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

No questions yet.

For anything that needs medical judgment, consult a doctor or pharmacist.

Related searches

Search tags

Suggested searches

This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.