Medication info

Ostem Lidocaine·Epinephrine Injection (1:100,000)

Prescription medication
Ingredient · strength
Lidocaine Hydrochloride Hydrate›21.33mg / 1mLEpinephrine Tartrate›0.018mg / 1mL
Manufacturer / importer
오스템파마주식회사
Appearance
A colorless cartridge-formed ampoule filled with a colorless transparent liquid
Packaging
50 cartridge ampoules (1.8 mL/cartridge ampoule x 50)
Approval status
Active

MFDS item code 202501805 · Approved 2025.07.15 · Insurance code 053500261

Summary

Main use
Effect of nerve block and infiltration anesthesia in dental areas
Who uses it
Adults
Adult dosage
For nerve block or infiltration anesthesia, use lidocaine hydrochloride at 6~40mg (this drug as 0.3~2mL). For oral surgery, use lidocaine hydrochloride at 60~100mg (this drug as 3~5mL).

Ingredients

Manufacturer
오스템파마주식회사

Efficacy & effects

Effect of nerve block and infiltration anesthesia in dental areas

View approved original text

During dental treatment, nerve block and infiltration anesthesia are mainly used to reduce pain. Nerve block involves injecting the drug around the nerve to block sensation over a wide area, while infiltration anesthesia involves directly injecting the drug into the tissue surrounding the treatment area to anesthetize only the local site. These two anesthesia techniques are used safely and effectively to reduce pain during dental procedures.

Dosage and Administration

Adult dosage

For nerve block or infiltration anesthesia, use lidocaine hydrochloride at 6~40mg (this drug as 0.3~2mL). For oral surgery, use lidocaine hydrochloride at 60~100mg (this drug as 3~5mL).

Precautions

This drug should not be used in certain patients. For example, patients with severe bleeding or shock, those with inflammation at the injection site or sepsis, and patients who are allergic to this drug or similar local anesthetics should avoid administration. Additionally, patients with hypertension, atherosclerosis, heart failure, hyperthyroidism, diabetes, and vascular spasms should exercise caution before using this drug. Administration should also be careful for patients with central nervous system diseases, pregnant women, elderly patients, patients with spinal deformities, and those taking certain anesthetics or antidepressants. This drug contains components that may cause allergic reactions, so caution is especially necessary for patients with asthma. During administration, side effects such as shock, hypotension, arrhythmias, and respiratory depression may occur, so the patient's condition should be closely monitored. Rarely, a severe symptom known as malignant hyperthermia may appear, and if such symptoms occur, administration should be stopped immediately, and appropriate treatment should be provided. Central nervous system-related symptoms may include tremors, convulsions, drowsiness, dizziness, and nausea, requiring attention. Hypersensitivity reactions such as rashes or swelling may also occur, so any abnormal symptoms should be reported immediately. When using this drug, always be prepared for emergencies and administer the minimum effective dose slowly for safety. The safety of this drug during pregnancy has not been established, so it should be used cautiously only when the benefits of treatment outweigh the risks. The elderly may be more sensitive to the components of this drug, so the patient's condition should be thoroughly verified before administration, and dosages should be adjusted accordingly. Finally, this drug is not intended for ophthalmic use, so caution is advised.

Side effects and when to seek care immediately

Serious side effects

  • Shock
  • hypotension
  • facial pallor
  • arrhythmias
  • respiratory depression
  • malignant hyperthermia
  • tachycardia
  • arrhythmia
  • blood pressure fluctuations
  • rapid temperature rise
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  • muscle rigidity
  • cyanosis
  • hyperventilation
  • sweating
  • acidosis
  • hyperkalemia
  • myoglobinuria
  • renal failure
  • convulsions
  • anaphylactic reactions

Mild side effects

  • Tremors
  • drowsiness
  • anxiety
  • agitation
  • numbness
  • dizziness
  • nausea
  • vomiting
  • urticaria
  • edema

Not everyone experiences these, and they can vary from person to person.

Storage

This drug is sensitive to light, so it should be stored in a tightly sealed container that does not allow light to enter. The appropriate storage temperature is a cool place between 1 to 25 degrees.

Appearance and packaging

Appearance

A colorless cartridge-formed ampoule filled with a colorless transparent liquid

Package unit

50 cartridge ampoules (1.8 mL/cartridge ampoule x 50)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.