Empagliflozin and Metformin Hydrochloride Tablets 5/850 mg (Empagliflozin, Metformin Hydrochloride)

Adult dose

The recommended dose of this medication is 1 tablet taken twice daily. It should be determined based on each patient's current treatment regimen, efficacy, and tolerability, not exceeding a total of 25 mg of empagliflozin and 2000 mg of metformin. For patients who cannot achieve sufficient blood sugar control with metformin alone or in combination with other medications such as insulin, the recommended dose is 5 mg of empagliflozin taken twice daily (a total of 10 mg per day).

This medication is used in the treatment of diabetes and helps lower blood sugar levels. It can cause a rare but serious side effect known as lactic acidosis; therefore, it should not be used by patients with poor kidney function or certain acute diseases. In addition, when used with other diabetes medications such as insulin or sulfonylureas, the risk of hypoglycemia may increase, so caution is advised. Patients with weakened kidney function or the elderly should regularly undergo kidney function tests, and if kidney function declines significantly, the use of this medication should be discontinued. During the use of this medication, if there is a sudden change in physical condition such as dehydration, severe infection, or surgery, it may be necessary to temporarily stop taking the medication. This medication may cause urinary tract infections or genital infections, so if symptoms of infection appear, immediate consultation with medical personnel is required. Gastrointestinal disturbances such as nausea, vomiting, and diarrhea may occur during use, and vitamin B12 deficiency may develop, so confirmation through blood tests may be necessary if needed. Women who are pregnant, potentially pregnant, or breastfeeding should not take this medication. Furthermore, alcohol consumption may increase the risk of side effects from this medication, so it is advisable to avoid it. This medication can cause water loss and drop in blood pressure, so caution is needed, especially for hypertensive patients or the elderly. If any unusual symptoms or suspected side effects occur during treatment, immediate consultation with a physician is recommended, and regular check-ups should be conducted for safe use.

Serious side effects

• Hives
• severe swelling (angioedema)
• ketoacidosis
• lactic acidosis
• necrotizing fasciitis
• pyelonephritis
• urosepsis
• acute kidney injury
• cerebral infarction
• myocardial infarction

Mild side effects

• Hypoglycemia
• urinary tract infection
• genital infection
• increased urination
• nausea
• vomiting
• diarrhea
• abdominal pain
• loss of appetite
• constipation

This medication is prone to be affected by air or moisture, so it must be stored in a tightly sealed container. The storage temperature should ideally be maintained at room temperature between 1 to 30 degrees Celsius.

Appearance

Yellow-tinged white, double-convex oval film-coated tablet

Package unit

60 tablets/bottle, 60 tablets/box [10 tablets/PTP x 6]