Hudiang Duo Controlled Release Tablet 5/1000 mg (Empagliflozin, Metformin)

Adult dose

The dosage of this medication is determined within the range of a maximum daily dose of 25 mg of empagliflozin and 2000 mg of extended-release metformin hydrochloride, considering each patient's current treatment regimen, efficacy, and tolerability. This medication should be taken once daily in the evening with meals to reduce gastrointestinal side effects caused by metformin. This extended-release formulation of 10/1000 mg or 25/1000 mg is to be administered.

This medication is used to treat type 2 diabetes and helps lower blood sugar levels. While taking this medication, caution is required as a rare side effect, severe lactic acidosis, can occur. Lactic acidosis can lead to an excessive accumulation of lactate in the body, which can result in a dangerous condition and potentially lead to death. Additionally, taking this medication with other diabetes drugs may cause hypoglycemia, so careful monitoring of blood sugar levels is necessary. Patients with moderate to severe renal impairment, acute kidney issues, severe infection, or heart disease should not use this medication. Women who are pregnant or may become pregnant, patients with liver dysfunction, or patients in poor nutritional status should also avoid taking this medication. This medication contains lactose, so patients with lactose intolerance should refrain from taking it. During treatment, regular kidney function tests should be conducted, and especially elderly patients or those with slightly impaired kidney function should be tested more frequently. Patients at risk of reduced fluid volume, for instance, those with dehydration symptoms or severe vomiting or diarrhea, should take this medication with caution. This medication may increase the risk of genital infections and urinary tract infections; if such symptoms occur, medical professionals should be informed immediately. Vitamin B12 levels may decrease, so patients taking this medication long-term should have their vitamin B12 levels checked regularly. Alcohol consumption may increase the risk of side effects from this medication, so it is advisable to avoid excessive drinking while on this treatment. Patients scheduled for surgery must stop taking this medication at least 48 hours before surgery and should resume only after kidney function has returned to normal post-surgery. This medication should be swallowed whole without breaking, crushing, or chewing; the tablet coating may be excreted but this is normal. While taking this medication, if symptoms of hypoglycemia, lactic acidosis (such as fatigue, muscle pain, difficulty breathing, abdominal pain), or infection appear, consulting a doctor promptly is necessary. Elderly patients require particular attention, and it is customary not to administer the maximum dose. In cases of overdose, seek immediate medical attention and proper treatment, which may include blood dialysis.

Serious side effects

• Hives
• severe swelling (angioedema)
• chest tightness
• difficulty breathing
• cold sweat
• paleness
• severe rash with fever
• blistering
• skin peeling
• pain in oral/eye mucosa

Mild side effects

• Hypoglycemia
• urinary tract infection
• genital infection
• increased urination
• nausea
• vomiting
• diarrhea
• abdominal pain
• loss of appetite
• constipation

This medication should be stored in a tightly sealed container to prevent air or moisture from entering, ideally at room temperature between 1 and 30 degrees Celsius. Storing it this way maintains the drug's effectiveness and prevents degradation.

Appearance

Gray, biconvex, oval-shaped controlled release film-coated tablet

Package unit

30 tablets/bottle