Roget Tablet 10/2.5mg (Ezetimibe, Rosuvastatin)

Adult dose

This drug is administered once daily, regardless of meals. The dosage range is 10/2.5mg to 10/20mg per day. The recommended initial dose is 10/2.5mg or 10/5mg per day. For patients requiring more substantial reduction of LDL cholesterol, the dosage may be adjusted accordingly. After initiation of treatment or adjustment of dosage, blood lipid levels should be checked at intervals of at least 4 weeks and adjusted as needed.

This drug has been reported to cause a rare side effect called rhabdomyolysis, which can lead to serious muscle abnormalities. Therefore, if severe muscle pain or weakness occurs, immediate consultation with a physician is needed. This drug should not be administered to patients with poor liver function, severely impaired kidney function, muscle diseases, or to women who are pregnant or breastfeeding. Care is particularly necessary when co-administering with certain medications in patients with severe renal impairment. Patients with a history of alcoholism or liver disease should also be cautious when using this drug. This drug may elevate liver enzyme levels, so regular liver function tests should be performed before and during treatment. If symptoms of muscle pain, cramps, weakness, fatigue, fever, etc. appear during treatment, inform a physician immediately for examination. This drug may increase blood glucose levels, but since the cardiovascular disease prevention effect is greater, appropriate diabetes management may be necessary when needed. This drug may interact with other medications, so if you are taking other drugs, you must inform your physician or pharmacist. Women who may become pregnant should use appropriate contraception while taking this drug and discontinue use immediately if pregnancy occurs. Safety in children and adolescents has not been sufficiently established, so use is not recommended. Caution should be taken when using this drug in the elderly due to a higher risk of muscle abnormalities. In case of overdose, as there is no specific antidote, appropriate treatment and support therapy according to the symptoms are necessary, and liver function and muscle enzyme tests should be performed. This drug contains lactose and should not be taken by patients with lactose intolerance. During the use of this drug, dietary measures and lifestyle improvements should be continued, and regular blood lipid tests should be conducted to monitor treatment effects and side effects.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, peeling skin, pain in mouth/eye mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, lightning headache, seizure, altered consciousness, visual disturbances, paralysis, urination issues.

Mild side effects

• Headache
• migraine
• sensory loss
• aphthous ulcer
• chronic gastritis
• muscle pain
• gout
• increased C-reactive protein
• nasopharyngitis
• arthralgia

This drug should be stored in a tightly sealed container to prevent air or moisture from entering. It is advisable to store it at room temperature, between 1 to 30 degrees Celsius. Proper storage helps maintain the drug's efficacy.

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle, 30 tablets/box [(10 tablets/PTP x 3, Alu-Alu)]