Donetiasan 5 mg (Donepezil Hydrochloride Hydrate), Donetiasan 10 mg (Donepezil Hydrochloride Hydrate)

Adult dose

As Donepezil Hydrochloride, take 1 sachet (5 mg of Donepezil Hydrochloride) once daily at bedtime. Administer doses of 1 sachet (5 mg of Donepezil Hydrochloride) for 4-6 weeks. After assessing clinical response, increase to 1 sachet (10 mg of Donepezil Hydrochloride). Underweight elderly women (85 years or older) should not exceed 1 sachet (5 mg of Donepezil Hydrochloride) daily. This drug should be taken with water.

Child dose

There is no dosing information available as there is no experience using it in children.

This drug contains Donepezil Hydrochloride as its main ingredient and is primarily used for the treatment of Alzheimer's type dementia. People with allergies to Donepezil or other components of this drug, pregnant women or women who may become pregnant, and breastfeeding women should not use this drug. Patients with heart disease, especially those with bradycardia or heart conduction disorders, should use this drug with caution as it may affect heart rhythm. Patients taking non-steroidal anti-inflammatory drugs or with a history of peptic ulcers should be cautious as there is a risk of gastrointestinal bleeding or exacerbation of ulcers. Patients with asthma or obstructive pulmonary disease should be cautious, as this drug may induce bronchoconstriction, worsening their symptoms. Patients with extrapyramidal disorders like Parkinson's disease should take this drug under medical supervision as it may exacerbate symptoms. Various adverse reactions may occur when taking this drug; in severe cases, fainting, heart problems, gastrointestinal bleeding, liver dysfunction, cerebrovascular issues, muscle abnormalities, respiratory difficulties, acute pancreatitis, and acute kidney failure have been reported. Common side effects may include nausea, vomiting, diarrhea, loss of appetite, dizziness, insomnia, hallucinations, anxiety, palpitations, rashes, muscle pain, headaches, and fatigue. While this drug can help improve symptoms of dementia, it should be considered to discontinue if there is no therapeutic effect, and regular medical evaluations during use are important. Patients with heart health issues or electrolyte imbalances must consult a doctor before taking this medication, and an ECG may be required in some cases. This medication may affect liver and kidney function, so regular monitoring is recommended. Be cautious while driving or operating machinery as attentiveness may be reduced due to side effects of this drug. This drug may interact with other medications, so particularly when taken together with antibiotics, antidepressants, antiarrhythmics, antipsychotics, and anti-inflammatory drugs, consultation with a doctor or pharmacist is essential. Pregnant or breastfeeding women should avoid this drug; if it is necessary to take, a professional consultation is advised, and breastfeeding may need to be discontinued. Safety in children has not been established, so it is not used in pediatric patients. In cases of overdose, severe symptoms such as vomiting, bradycardia, hypotension, respiratory depression, and seizures may occur, and immediate medical attention is required. This medication should not be divided, and it should be stored out of reach of children. Transferring to another container may lead to degradation of quality, so caution is needed.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, mucosal pain in mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, cough with fever and respiratory abnormalities, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headaches, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urine

Mild side effects

• Nausea
• vomiting
• diarrhea
• loss of appetite
• headaches
• fatigue
• dizziness
• insomnia
• hallucinations
• agitation

This medication is sensitive to light and should be stored in a light-resistant container. Additionally, it is important to keep it at room temperature between 1°C and 30°C to maintain its effectiveness.

Appearance

White or light yellow powder

Package unit

Donetiasan 5 mg - 30 sachets/box, Donetiasan 10 mg - 30 sachets/box