Amoprel Tablet 1.67/16.67/4.17 Milligrams (Amlodipine, Losartan, Chlorthalidone)

Adult dose

As an initial therapy for patients with essential hypertension, take 1 tablet once daily, regardless of meals. It is recommended to take it at the same time every day, if possible (e.g., in the morning).

This medication is a combination antihypertensive agent with three ingredients that helps lower blood pressure. This medicine should not be used during pregnancy, as it can cause serious harm to the fetus; if pregnancy is confirmed, use should be discontinued immediately. Patients with impaired liver function or severe liver disease may experience serious side effects such as hepatic encephalopathy when taking this medication, so caution is needed. In patients with severely impaired kidney function, this medication should be avoided as it may further degrade kidney function. This medication should not be taken in cases of known allergy to any of its ingredients or similar medications, or in cases of severe hypotension or serious liver or kidney diseases. Elderly patients, those with high potassium levels, and dialysis-dependent renal failure patients should use this drug cautiously and be mindful to avoid excessively low blood pressure. During treatment, regular monitoring of blood pressure, kidney function, and electrolyte levels should be conducted to check for abnormalities. Possible side effects of this medication include dizziness, headache, fatigue, dyspepsia, and cough, with rare occurrences of severe allergic reactions or liver dysfunction. If sudden drops in blood pressure or severe side effects occur during treatment, consult a physician immediately. This medication's effectiveness may be enhanced when used with other antihypertensive drugs, so inform your physician about any other medications being taken. Pregnant or nursing women should avoid using this drug, and if it must be used, a careful decision should be made in consultation with a healthcare professional. Children under 18 years of age are not recommended for use, as the safety and efficacy of this medication in this population have not been established. In cases of overdose, severe hypotension, rapid heartbeat, and coma may occur; immediate emergency care is necessary. Store this medication in a sealed container to protect it from air and moisture and keep it at room temperature between 1 to 30 degrees Celsius. Therefore, it is important to avoid direct sunlight and not store it in excessively hot or cold places.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, peeling skin, pain in oral/eye mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities with cough and fever, jaundice (yellowing of the skin or eyes), extreme lethargy, sudden and severe headaches, thunderclap headaches, seizures, confusion, visual disturbances, paralysis, urination change.

Mild side effects

Headache, dizziness, migraine, upper abdominal pain, diarrhea, dyspepsia, nausea, cough, rhinitis, rash, pruritus, dermatitis, contact dermatitis, increase in blood thyroid-stimulating hormone, weight loss, dyslipidemia, hyperlipidemia, arthralgia, back pain, myalgia, palpitations, eye hemorrhage, bruising, low back pain, leg pain, knee pain, muscle weakness, lumbar radiculopathy, nasopharyngitis, upper respiratory tract infection, urinary tract infection, transient hoarseness.

This medication should be stored in a sealed container to protect it from air or moisture, and it is best kept at room temperature between 1 to 30 degrees Celsius. Consequently, it is important to avoid direct sunlight and not to place it in excessively hot or cold areas.

Appearance

Pink round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle