Medication info
Wecap 20 mg (Fexuprazan Hydrochloride)

Wecap 20 mg (Fexuprazan Hydrochloride)

Prescription medicationTabletOral
Ingredient · strength
Fexuprazan Hydrochloride›20mg / 1 tablet
Manufacturer / importer
Daewoong Bio Co., Ltd.
Appearance
Pale yellow film-coated tablet in an elongated shape
Packaging
28 tablets/bottle, 100 tablets/bottle, 300 tablets/bottle, 28 tablets/box [7 tablets/PTPx4]
Approval status
Active

MFDS item code 202501243 · Approved 2025.05.20 · Insurance code 694004550

Summary

Main use
Prevention of anti-inflammatory analgesic-induced peptic ulcers
Who takes it
Adults
Adult dose
Prevention of nonsteroidal anti-inflammatory drug (NSAID)-induced peptic ulcers (gastric and duodenal ulcers) Administer 20mg orally once daily for 24 weeks. The duration of the comparative clinical trial did not exceed 24 weeks. This medicine may be administered without regard to meals.

Ingredients

Manufacturer
Daewoong Bio Co., Ltd.

Efficacy & effects

Prevention of anti-inflammatory analgesic-induced peptic ulcers

  • NSAID-induced peptic ulcers
  • gastric ulcers
  • duodenal ulcers
View approved original text

This medication is used to prevent peptic ulcers that may occur in the stomach and duodenum in patients taking non-steroidal anti-inflammatory drugs (NSAIDs).

How to take

Adult dose

Prevention of nonsteroidal anti-inflammatory drug (NSAID)-induced peptic ulcers (gastric and duodenal ulcers) Administer 20mg orally once daily for 24 weeks. The duration of the comparative clinical trial did not exceed 24 weeks. This medicine may be administered without regard to meals.

Precautions

This medication should not be used in patients who have experienced allergies or hypersensitivity to this medication or any of its components. Additionally, this medication is contraindicated in patients taking certain antiviral agents, namely atazanavir, nelfinavir, and rilpivirine. It is advisable for pregnant or breastfeeding women to avoid this medication, and its use is particularly not recommended during pregnancy. Since this medication contains lactose, patients with genetic issues such as lactose intolerance, lactase deficiency, or glucose-galactose malabsorption should avoid taking it. Patients with liver or kidney function problems have limited experience with this medication and should use it cautiously. Elderly patients may have decreased liver and kidney function, hence should use it with care. This medication is used for the prevention of gastric or duodenal ulcers caused by NSAIDs, but there is a slight increase in the risk of gastrointestinal infections, so consultation with a doctor is recommended if diarrhea persists. Long-term use may increase the risk of fractures related to osteoporosis; thus, appropriate monitoring including bone density testing is necessary if needed. In cases of long-term use beyond 3 months, hypomagnesemia can occur, so it is advisable to regularly check magnesium levels. This medication suppresses gastric acid, which may affect the absorption of other medications; therefore, caution is advised when used in combination with certain drugs, and patients should inform their doctor of any other medications being taken. Pregnant or breastfeeding women should discontinue breastfeeding when taking this medication, and the safety and efficacy in children and adolescents have not been established. No severe side effects have been reported in cases of overdose; however, patients' conditions should be closely monitored, and necessary treatment should be provided if overdose occurs. Lastly, this medication should be stored out of reach of children, and it is advisable not to transfer it to another container.

Side effects

  • Dyspepsia
  • diarrhea
  • erosive gastritis
  • epigastric pain
  • nausea
  • abdominal discomfort
  • vomiting
  • abdominal distension
  • constipation
  • enteritis
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  • abdominal pain
  • gastroesophageal reflux disease
  • hypergastrinemia
  • bloating
  • colonic polyps
  • mesenteric artery dissection
  • COVID-19
  • nasopharyngitis
  • herpes zoster
  • influenza
  • cystitis
  • acute pyelonephritis
  • coronavirus infection
  • gastritis
  • paronychia
  • tinea
  • upper respiratory tract infection
  • arthralgia
  • joint swelling
  • limb pain
  • rheumatoid arthritis
  • arthritis
  • chondropathy
  • muscle weakness
  • myofascial pain syndrome
  • osteoarthritis
  • tendinitis
  • increased blood gastrin
  • increased alanine aminotransferase
  • increased aspartate aminotransferase
  • increased blood creatine kinase
  • increased blood triglycerides
  • QT interval prolongation on ECG
  • urticaria
  • dermal cyst
  • eczema
  • psoriasis
  • rash
  • chest pain
  • peripheral edema
  • catheter site pain
  • inflammation
  • fever
  • foreign body sensation
  • cough
  • pharyngodynia
  • idiopathic pulmonary fibrosis
  • pneumothorax
  • lung mass
  • reflux laryngitis
  • contusion
  • ligament sprain
  • epicondylitis
  • lower limb fracture
  • meniscal injury
  • procedure-related pain
  • chronic kidney disease
  • hypertension
  • atherosclerosis
  • hypertensive emergency
  • neutropenia
  • thrombocytopenia
  • sleep disorders
  • allergic conjunctivitis
  • dyslipidemia
  • hypertriglyceridemia
  • autoimmune hepatitis
  • acute hepatitis
  • abnormal uterine bleeding
  • thyroid cyst
  • tinnitus

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to protect it from air and moisture. It is best kept at room temperature, between 1°C and 30°C.

Appearance and packaging

Appearance

Pale yellow film-coated tablet in an elongated shape

Package unit

28 tablets/bottle, 100 tablets/bottle, 300 tablets/bottle, 28 tablets/box [7 tablets/PTPx4]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.