Fexuclu Tablet 20 mg (Fexuprazan Hydrochloride)

Adult dose

Prevention of nonsteroidal anti-inflammatory drug (NSAID)-induced peptic ulcers (gastric and duodenal ulcers) Administer 20mg orally once daily for 24 weeks. The duration of the comparative clinical trial did not exceed 24 weeks. This drug may be administered regardless of meals.

This medication should not be used in patients who have an allergy to this drug or its components, or who have experienced hypersensitivity reactions. Additionally, this drug should not be administered to patients taking specific antiviral medications such as Atazanavir, Nelfinavir, or Rilpivirine. Women who are pregnant or breastfeeding should also not use this medication, and special caution is necessary if pregnant as it may affect the fetus. This medication contains lactose, therefore it should not be given to patients with lactose intolerance or hereditary lactose metabolism disorders. Safety and efficacy of this drug have not been sufficiently established in patients with impaired liver or kidney function, and it should be used cautiously in such cases. In the elderly, there may be decreased liver and kidney function, hence caution is needed during administration. There may be a slightly increased risk of gastrointestinal infections when taking this medication, and if diarrhea persists, a doctor should be consulted. Long-term or high-dose use may increase the risk of fractures associated with osteoporosis, so regular monitoring of bone health is advisable when necessary. Taking this medication for more than three months may cause hypomagnesemia, therefore regular checks of magnesium levels are necessary. It is used for the prevention of gastric ulcers in patients taking non-steroidal anti-inflammatory drugs (NSAIDs), and a history of gastric ulcers should be confirmed before administration. As this drug may interact with other medications, particularly specific antiviral agents or antibiotics, consulting a physician or pharmacist is advised when taking it with NSAIDs. It is safest for pregnant or breastfeeding women not to take this medication, and breastfeeding should be discontinued if taking it. Safety and efficacy in children and adolescents have not been sufficiently studied, hence use is not recommended. No serious side effects have been reported with overdose; however, in case of overdose, medical assistance should be sought immediately for appropriate treatment. This medication should be kept out of reach of children, and transferring it to another container may lead to deterioration in quality or accidents, so caution is advised.

Dyspepsia, diarrhea, erosive gastritis, upper abdominal pain, nausea, abdominal discomfort, vomiting, abdominal distension, constipation, enteritis, abdominal pain, gastroesophageal reflux disease, hypergastrinemia, meteorism, colon polyps, mesenteric artery dissection, COVID-19, nasopharyngitis, herpes zoster, influenza, cystitis, acute pyelonephritis, coronavirus infection, gastroenteritis, paronychia, athlete's foot, upper respiratory infection, arthralgia, joint swelling, limb pain, rheumatoid arthritis, arthritis, chondropathy, muscle weakness, myofascial pain syndrome, osteoarthritis, tendinitis, increased blood gastrin, increased alanine aminotransferase, increased aspartate aminotransferase, increased blood creatine phosphokinase, increased blood triglycerides, prolonged QT interval on electrocardiogram, urticaria, dermoid cysts, eczema, psoriasis, rash, chest pain, peripheral edema, catheter site pain, inflammation, fever, foreign body sensation, cough, oropharyngeal pain, idiopathic pulmonary fibrosis, pneumothorax, lung mass, laryngopharyngeal reflux, contusion, ligament sprain, epicondylitis, lower extremity fracture, meniscus injury, procedure-related pain, chronic kidney disease, hypertension, arteriosclerosis, hypertensive crisis, neutropenia, thrombocytopenia, sleep disorders, allergic conjunctivitis, dyslipidemia, hypertriglyceridemia, autoimmune hepatitis, acute hepatitis, abnormal uterine bleeding, thyroid cysts, tinnitus

This medication should be stored in a tightly closed container to protect it from exposure to air and moisture. It is recommended to maintain a storage temperature between 1 and 30 degrees Celsius.

Appearance

Light yellow rectangular film-coated tablet

Package unit

28 tablets/bottle, 100 tablets/bottle, 300 tablets/bottle, 28 tablets/box [7 tablets/PTP x 4]