Medication info
Crevistar Tablets 2.5/5 mg (Nebivolol, Rosuvastatin)

Crevistar Tablets 2.5/5 mg (Nebivolol, Rosuvastatin)

Prescription medicationTablet경구
Ingredient · strength
Nebivolol Hydrochloride›5.45mg / 1 tabletRosuvastatin Calcium Micronized›20.8mg / 1 tablet
Manufacturer / importer
알리코제약(주)
Appearance
White to almost white round film-coated tablet
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 202501056 · Approved 2025.04.30 · Insurance code 656005750

Summary

Main use
Treatment of essential hypertension and hypercholesterolemia (reducing cardiovascular disease risk, etc.)
Who takes it
Adults
Adult dose
This medication is administered for the convenience of patients who are taking nebivolol and rosuvastatin simultaneously, with a dosage of one tablet per day.

Ingredients

Manufacturer
알리코제약(주)

Efficacy & effects

Treatment of essential hypertension and hypercholesterolemia (reducing cardiovascular disease risk, etc.)

  • Essential hypertension
  • chronic heart failure
  • primary hypercholesterolemia
  • heterozygous familial hypercholesterolemia
  • mixed dyslipidemia
  • homozygous familial hypercholesterolemia
  • hypercholesterolemia
  • primary dysbetalipoproteinemia
  • coronary heart disease
  • stroke
  • myocardial infarction
View approved original text

This medication is used as an alternative treatment for patients taking nebivolol and rosuvastatin simultaneously. Nebivolol primarily helps manage essential hypertension and mild to moderate chronic heart failure in elderly patients over 70 years old. Rosuvastatin is used to control hypercholesterolemia, especially familial hypercholesterolemia and mixed dyslipidemia, in conjunction with dietary and exercise therapies. It is also effective in reducing cardiovascular disease risk and contributes to lowering the risk of complications such as stroke, myocardial infarction, and complications after arterial revascularization. Thus, this medication is used to improve blood pressure and cardiovascular health and control blood cholesterol levels to lower cardiovascular risk.

How to take

Adult dose

This medication is administered for the convenience of patients who are taking nebivolol and rosuvastatin simultaneously, with a dosage of one tablet per day.

Precautions

This medication should not be used by patients who are allergic to its specific components. It should also not be taken by patients with severely impaired liver function or ongoing liver disease. Administration is contraindicated for patients with bradycardia or problems with heart conduction. Patients with acute heart failure or cardiogenic shock, where heart function has sharply deteriorated, should also avoid this medication. It may pose risks for patients with very low blood pressure or severe peripheral circulation disorders. Patients with severely impaired kidney function, a history of bronchial asthma or bronchospasm should also avoid this medication. It is not administered to women who are pregnant, breastfeeding, or of childbearing age without adequate contraception. Patients with a history of muscle disease or a high risk of myopathy should avoid high doses of this medication. This drug is not to be used by patients with certain genetic metabolic disorders, like lactose intolerance. Chronic pulmonary disease, untreated heart failure, peripheral circulation disorders, thyroid abnormalities, and diabetic patients should use this medication cautiously. Should symptoms of myalgia or myopathy occur, notify healthcare providers immediately and discontinue medication if needed. This medication can affect liver and kidney function, making regular testing necessary. In elderly patients, it is crucial to start at a low dose and monitor their condition closely. This medication can interact with other drugs, so it is vital to inform healthcare providers about any medications being taken. Women who could become pregnant must employ proper contraceptive methods before taking this medication, and should stop taking it immediately if pregnant. Women who are breastfeeding are also advised not to take this medication. In case of overdose, seek medical attention immediately for appropriate treatment, which may include cardiac rhythm control or blood pressure maintenance therapy. Dizziness can occur while taking this medication, so caution is advised when driving or operating machinery. Keep this medication out of the reach of children and store it in its original container to prevent quality deterioration.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, sweating, paleness, severe allergic reactions, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucous membranes, severe cutaneous adverse reactions, difficulty breathing or shortness of breath, asthma attacks, respiratory issues accompanied by cough and fever, jaundice (yellowing of the skin or eyes), profound lethargy, liver abnormalities (jaundice), sudden and

Mild side effects

  • Eye discharge
  • upper abdominal discomfort
  • gastritis
  • gastroesophageal reflux disease
  • chest pain
  • nasopharyngitis
  • influenza
  • CK increase
  • ALT increase
  • AST increase
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  • increased serum potassium
  • hyperkalemia
  • musculoskeletal chest pain
  • musculoskeletal pain
  • musculoskeletal stiffness
  • headache
  • dizziness
  • hematuria
  • hematoma
  • rash
  • vision impairment
  • bradycardia
  • AV block
  • AV conduction delay
  • hypotension
  • heart failure
  • intermittent claudication
  • sensory disturbances
  • depression
  • nightmares
  • syncope
  • diarrhea
  • constipation
  • nausea
  • dyspepsia
  • bloating

Not everyone experiences these, and they can vary from person to person.

Storage

Store this medication in a tightly sealed container to protect it from air and moisture. It is important to maintain storage temperatures between 1 degree and 30 degrees Celsius.

Appearance and packaging

Appearance

White to almost white round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.