MSPOLMIN Sustained Release Tablets 5/50/750 mg (Empagliflozin, Sitagliptin, Metformin)

Adult dose

The recommended dosage for this medication is 25 mg of empagliflozin and 100 mg of sitagliptin, with the sustained-release metformin hydrochloride not exceeding 2000 mg. It should be taken once daily at dinner, with gradual dosage adjustments. For 25/100/1000 mg and 10/100/1000 mg sustained-release tablets, take 1 tablet once daily. For 12.5/50/750 mg and 5/50/750 mg.

This medication contains sitagliptin, empagliflozin, and metformin. Firstly, the sitagliptin component can rarely cause serious allergic reactions, so if symptoms such as skin rash, difficulty breathing, or swelling of the face or neck occur after taking the medication, it should be discontinued immediately, and a doctor should be consulted. Moreover, sitagliptin can lead to acute pancreatitis, a serious side effect characterized by inflammation of the pancreas, so if symptoms such as abdominal pain, vomiting, or nausea occur, the patient should go to the hospital immediately. The metformin component can rarely cause lactic acidosis, a very dangerous condition, so if symptoms such as shortness of breath, muscle pain, fatigue, abdominal pain, or vomiting occur, the medication should be stopped immediately and emergency treatment sought. This medication should not be used in patients with type 1 diabetes, severely impaired kidney function, severe liver disease, acute heart failure, or serious infections or dehydration. Especially before and after tests using radiocontrast agents, this medication should be temporarily discontinued, and it should be resumed only after confirming normal kidney function post-examination. Elderly patients or those with slightly impaired kidney function should undergo regular kidney function tests, and dosage adjustment or discontinuation may be considered if necessary. This medication has glucose-lowering effects, so caution is needed when taken with insulin or other glucose-lowering agents, as hypoglycemic symptoms may occur. Additionally, this medication can increase the risk of genital infections and urinary tract infections, so prompt treatment should be sought if symptoms of infection arise. Symptoms of low blood pressure and dehydration can also occur due to fluid loss, so caution should be exercised to avoid dehydration from diarrhea or vomiting. If sudden joint pain or blistering skin conditions occur during medication use, a doctor should be informed immediately, and the medication may need to be discontinued if necessary. It is safe not to use this medication during pregnancy or in cases of severe liver dysfunction. While taking this medication, regular blood tests and physical examinations should be performed to monitor for adverse reactions, and if any abnormal symptoms occur, immediate consultation with medical personnel is recommended.

Serious side effects

Hives, severe swelling (edema), angioedema, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, sores in the mouth/eye mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances.

Mild side effects

• Hypoglycemia
• indigestion
• vomiting
• diarrhea
• abdominal pain
• sweating
• headache
• dizziness
• weakness
• rash

This medication may be sensitive to air and moisture, so it should be stored in a sealed container. Additionally, it is best to keep it at room temperature between 1°C and 30°C, avoiding extremely hot or cold conditions.

Appearance

Purple, oval, double convex, sustained-release film-coated tablets

Package unit

30 tablets/bottle, 60 tablets/bottle